Anti-ADAM2 Antibody Picoband®

Product Name

Anti-ADAM2 Antibody Picoband®

View all ADAM2 Antibodies

SKU/Catalog Number

PA2069
BA3029-2 is an alternative SKU for this antibody, used in previous lots.

Size

100 μg/vial

Form

Lyophilized

Description

ADAM2 (fertilin β) is a membrane-anchored disintegrin/metalloprotease implicated in sperm–egg interactions and other cell–cell/cell–matrix processes (from page background). Assay context: WB human samples using PA2069. In reproductive biology panels, may be evaluated alongside chromatin regulators like ARID2 to study germ cell differentiation (putative).

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ADAM2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2069)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM2.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2069 is reactive to ADAM2 in Human

Observed Molecular Weight

60 kDa

Calculated molecular weight

82.5 kDa

Background of ADAM2

ADAM2 (A Disintegrin and Metalloproteinase Domain 2) , also known as FTNB or PH30, is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Burkin et al. (1997) used fluorescence in situ hybridization to map the FTNB gene to 8p11.2.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2069 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: SMMC Cell

Validation Images & Assay Conditions

See full target information ADAM2

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