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- Table of Contents
Facts about Disintegrin and metalloproteinase domain-containing protein 2.
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Human | |
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Gene Name: | ADAM2 |
Uniprot: | Q99965 |
Entrez: | 2515 |
Belongs to: |
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No superfamily |
ADAM metallopeptidase domain 2; Cancer/testis antigen 15; CRYN2; CT15ADAM 2; disintegrin and metalloproteinase domain-containing protein 2; EC 3.4.24; fertilin beta; Fertilin subunit beta; FTNBCRYN1; PH-30; PH-30b; PH30PH30-beta
Mass (kDA):
82.457 kDA
Human | |
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Location: | 8p11.22 |
Sequence: | 8; NC_000008.11 (39743735..39838227, complement) |
Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
Membrane; Single-pass type I membrane protein.
There are several benefits of using Boster Bio: its flexibility, ease of use, and cost. If you are using the system for research purposes you should be aware of some optimization tips. We will be discussing the ADAM2 Marker and how it works, as well as the types of bacteria that you can use it for. Read on to learn more! Check out our ADAM2 Marker Optimization Guide to learn more on Boster Bio.
The ADAM2 gene is located on chromosome 8's p arm. It is located on two NCBI maps, the cytogenetic and the sequence maps. This information will be used to create a genetic map for the human genome. The map shows the position of ADAM2 and other genes on chromosome 8.
Different mammalian species may have different properties for the ADAM2 genes. Western blotting is not recommended for commercial antibodies against ADAM2. The ADAM2 genes is expressed in the brain and heart. It is found in blood, ear, bone, and other tissues in humans. It is expressed by both the male genitalia and the female genitalia in mammals. ADAM2 is a protein that is important in the immune system.
The protein has a large number of applications, including cancer research. The ADAM2 gene has been expressed in mouse testes. It is also immunoprecipitated in the urine and sperm of mice. It is particularly useful in the detection and treatment of cancer cells. This marker has also been used in other experimental studies. However, it is not commercially available and therefore is not widely used. Learn more about ADAM2 Marker in the publications below.
The ADAM2 gene is widely used in research and cancer research. It is expressed in both human and monkey germ cell. Anti-hADAM2-CyT antibodies were used to analyze testicular cells taken from monkeys. A protein sample can then be reduced using this antibody in an 10% resolving solution. B-ME is the chemical name for b-mercaptoethanol, which is used in the gel.
IHB staff must conduct thorough research to complete the application process. But, submitting a Marker application does not guarantee approval for your project. IHB staff carefully reviews each application. The quality of your application will determine whether or not your application is accepted for the final review phase. While the number of markers installed in 2022 is still growing, the overall success rate of the project depends on the quality of applications submitted in 2022.
The ADAM2 gene encodes three proteins, the prodomain (also known by metalloprotease), disintegrin (D), and the cysteine rich domain. The cytoplasmic tail includes the Cys domain. Anti-hADAM2-CyT antibody binds to the Cys domain of ADAM2.
PMID: 9041139 by Vidaeus C.M., et al. Human fertilin beta: identification, characterization, and chromosomal mapping of an ADAM gene family member.
PMID: 8702389 by Gupta S.K., et al. Molecular cloning of the human fertilin beta subunit.