Anti-Angiotensin Converting Enzyme 1/ACE Antibody Picoband®

Product Name

Anti-Angiotensin Converting Enzyme 1/ACE Antibody Picoband®

View all ACE Antibodies

SKU/Catalog Number

PA2196-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Angiotensin Converting Enzyme 1/ACE Antibody catalog # PA2196-2. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Angiotensin Converting Enzyme 1/ACE Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2196-2)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Angiotensin Converting Enzyme 1, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2196-2 is reactive to ACE in Human, Mouse

Observed Molecular Weight

150 kDa

Calculated molecular weight

149.7 kDa

Background of ACE

Angiotensin I converting enzyme (ACE), also called DCP or CD143 is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. This gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2196-2 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse

Positive Control

WB: A549 Whole Cell, HELA Whole Cell, 22RV1 Whole Cell

Validation Images & Assay Conditions

See full target information ACE

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