Many biological assays use antibodies to detect ACE, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACE in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACE antibodies...
We validate the specificity of these antibodies to ACE by testing them on tissues known to express ACE positively and negatively. Browse below to find the ACE antibody that suites your experiment. We have 100 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Designing a Western blot for ACE?
The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator.
Has also a glycosidase activity that releases GPI-anchored proteins from the membrane by cleaving the mannose linkage from the GPI moiety. .
Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.
Subcellular Localizations
[Angiotensin-converting enzyme, soluble form]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm. Detected in both cell membrane and cytoplasm in neurons.
Diseases
Hypertensive Disease
Heart Failure
Diabetes Mellitus
Kidney Diseases
Myocardial Infarction
Infarction
Cardiovascular Diseases
Hypertrophy
Heart Diseases
Diabetes Mellitus, Non-insulin-dependent
Kidney Failure, Chronic
Diabetic Nephropathy
Kidney Failure
Proteinuria Of Undiagnosed Cause
Essential Hypertension
Coronary Heart Disease
Cerebrovascular Accident
Left Ventricular Hypertrophy
Coronary Artery Disease
Ventricular Dysfunction, Left
Pathways
Excretion
Pathogenesis
Glomerular Filtration
Vasoconstriction
Secretion
Vasodilation
Localization
Transport
Aging
Reflex
Cell Proliferation
Natriuresis
Coagulation
Virulence
Angiogenesis
Regulation Of Blood Pressure
Cell Growth
Diuresis
Fibrinolysis
Platelet Aggregation
PTMs
Cleavage
Nitration
Phosphorylation
Glycosylation
Oxidation
Reduction
Acetylation
Carboxylation
Biotinylation
Iodination
Deglycosylation
Methylation
Amidation
Dephosphorylation
Acylation
Gpi Anchoring
Hydroxylation
Demethylation
Ribosylation
Deacetylation
For details, visit: bosterbio.com/bosterbio-gene-info-cards/ACE
References
PMID: 2849100 by Soubrier F., et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.
PMID: 2547653 by Lattion A.L., et al. The testicular transcript of the angiotensin I-converting enzyme encodes for the ancestral, non-duplicated form of the enzyme.
92 Publications of Boster ACE Antibodies & ELISA Kits
PubMed ID: PMID:30210698, Identification and differentiation therapy strategy of pterygium in vitro