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Product Info Summary
| SKU: | A06783-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-APBA2 Antibody
SKU/Catalog Number
A06783-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-APBA2 Antibody (Catalog # A06783-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
APBA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-APBA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06783-1)
Host
Rabbit
Contents
APBA2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
APBA2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APBA2. The immunogen is located within amino acids 290 - 340 of APBA2.
Reactive Species
A06783-1 is reactive to APBA2 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
82.5 kDa
Background of APBA2
APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06783-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
APBA2 antibody can be used for detection of APBA2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of APBA2 in human brain tissue lysate with APBA2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of APBA2 in human brain tissue with APBA2 antibody at 10 μg/mL.
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Immunofluorescence of APBA2 in human brain tissue with APBA2 antibody at 20 μg/mL.
Specific Publications For Anti-APBA2 Antibody (A06783-1)
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