Anti-APC10 ANAPC10 Antibody

Apc10 antibody

Boster Bio Anti-APC10 ANAPC10 Antibody (Catalog # A07065). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A07065
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

Product Name

Anti-APC10 ANAPC10 Antibody

View all Apc10 Antibodies

SKU/Catalog Number

A07065

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-APC10 ANAPC10 Antibody (Catalog # A07065). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

APC10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-APC10 ANAPC10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07065)

Host

Rabbit

Contents

APC10 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

APC10 antibody was raised against a 16 amino acid synthetic peptide near the center of human APC10. The immunogen is located within amino acids 60 - 110 of APC10.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.

Reactive Species

A07065 is reactive to ANAPC10 in Human, Mouse, Rat

Applications

A07065 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

21.252kDa

Background of Apc10

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC10 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. It has been suggested that APC10 plays a role to regulate the binding of specific substrates to the APC/C complex, similar to that of coactivators.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

APC10 antibody can be used for detection of APC10 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ANAPC10 (Source: Uniprot.org, NCBI)

Gene Name

ANAPC10

Full Name

Anaphase-promoting complex subunit 10

Weight

21.252kDa

Superfamily

APC10 family

Alternative Names

anaphase promoting complex subunit 10; anaphase-promoting complex subunit 10; APC10DOC1; Cyclosome subunit 10; DKFZP564L0562 ANAPC10 APC10, DOC1 anaphase promoting complex subunit 10 anaphase-promoting complex subunit 10|cyclosome subunit 10

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ANAPC10, check out the ANAPC10 Infographic

ANAPC10 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ANAPC10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A07065-0.1 mg

0.1 mg

$449

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