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Product Info Summary
| SKU: | A11671-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-APPBP2 Antibody
SKU/Catalog Number
A11671-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-APPBP2 Antibody (Catalog # A11671-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
APPBP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-APPBP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11671-1)
Host
Rabbit
Contents
APPBP2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2. The immunogen is located within the last 50 amino acids of APPBP2.
Cross-reactivity
APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist; this antibody will detect both isoforms.
Reactive Species
A11671-1 is reactive to APPBP2 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
66.9 kDa
Background of APPBP2
The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11671-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
APPBP2 antibody can be used for detection of APPBP2 by Western blot at 0.5 - 1 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of APPBP2 in human brain tissue lysate with APPBP2 antibody at (A) 0.5 and (B) 1 μg/ml.
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Immunohistochemistry of APPBP2 in human brain tissue with APPBP2 antibody at 5 μg/mL.
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Immunofluorescence of APPBP2 in human brain tissue with APPBP2 antibody at 20 μg/mL.
Specific Publications For Anti-APPBP2 Antibody (A11671-1)
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