APPBP2 Antibodies

AND APPBP2 ELISA kits, APPBP2 Proteins

Many biological assays use antibodies to detect APPBP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with APPBP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop APPBP2 antibodies...

We validate the specificity of these antibodies to APPBP2 by testing them on tissues known to express APPBP2 positively and negatively. Browse below to find the APPBP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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APPBP2 Infographic by Boster Bio

All APPBP2 Products

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Anti-APPBP2 Antibody

Western blot analysis of APPBP2 in human brain tissue lysate with APPBP2 antibody at (A) 0

Immunohistochemistry of APPBP2 in human brain tissue with APPBP2 antibody at 5 μg/mL

Immunofluorescence of APPBP2 in human brain tissue with APPBP2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A11671-1
0.1 mg

APPBP2 Overview

Facts about Amyloid protein-binding protein 2.

APPBP2 3D structure. Source: alphafold

Amyloid protein-binding protein 2 (APPBP2)

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the surface.

Gene Information

Human
Gene Name:	APPBP2
Uniprot:	Q92624
Entrez:	10513

Family

Belongs to:

No superfamily

Alternative Names

amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; amyloid protein-binding protein 2; APP-BP2; KIAA0228HS.84084; PAT1amyloid beta precursor protein (cytoplasmic tail)-binding protein 2; Protein interacting with APP tail 1

Molecular Weight

Mass (kDA):
66.853 kDA

Genomic Context


Human

Location:	17q23.2
Sequence:	17; NC_000017.11 (60443149..60526242, complement)

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Associated with membranes and microtubules.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Desmoplastic
Neuroblastoma
Adenocarcinoma
Malignant Neoplasm Of Prostate
Neoplasm Metastasis
Cerebellar Neoplasms
Desmoplastic Medulloblastoma
Malignant Neoplasm Of Breast
Infertility
Hypokinesia

Prostatic Neoplasms
Leukemia
Mammary Neoplasms
Medulloblastoma
Ovarian Neoplasm
Cytogenetic Abnormality
Adenocarcinoma, Clear Cell

Pathways

Pathogenesis
Dna Amplification
Cell Death
Endocytosis
Receptor Transactivation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APPBP2

References

PMID: 9843960 by Zheng P., et al. PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.

PMID: 11742091 by Gao Y., et al. The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus.