Product Info Summary
SKU: | A07968T363 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-ARHGAP17 (T363) Antibody
SKU/Catalog Number
A07968T363
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ARHGAP17 (T363) Antibody catalog # A07968T363. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ARHGAP17 (T363) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07968T363)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of humanRHG17.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07968T363 is reactive to ARHGAP17 in Human, Mouse, Rat
Applications
A07968T363 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
95.437kDa
Background of ARHGAP17
Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
Richnau N., J. Biol. Chem. 276:35060-35070(2001).
Ota T., Nat. Genet. 36:40-45(2004).
The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ARHGAP17 (Source: Uniprot.org, NCBI)
Gene Name
ARHGAP17
Full Name
Rho GTPase-activating protein 17
Weight
95.437kDa
Alternative Names
DKFZp564A1363; FLJ10308; FLJ13219; FLJ37567; FLJ43368; MGC87805; MST110; MSTP038; MSTP066; MSTP110; NADRIN; neuron-associated developmentally regulated protein; PP367; PP4534; Rho GTPase activating protein 17; rho GTPase-activating protein 17; RhoGAP interacting with CIP4 homologs 1; RhoGAP interacting with CIP4 homologs protein 1; Rho-type GTPase-activating protein 17; RICH-1; RICH1B; RICH1MST066; WBP15 ARHGAP17 MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH-1, RICH1, WBP15 Rho GTPase activating protein 17 rho GTPase-activating protein 17|RhoGAP interacting with CIP4 homologs 1|neuron-associated developmentally regulated protein|rho-type GTPase-activating protein 17
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARHGAP17, check out the ARHGAP17 Infographic
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In this infographic, you will see the following information for ARHGAP17: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ARHGAP17 (T363) Antibody (A07968T363)
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No publications found for A07968T363
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