Anti-ARMER ARL6IP1 Antibody

Product Name

Anti-ARMER ARL6IP1 Antibody

View all ARL6IP1 Antibodies

SKU/Catalog Number

A08487

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ARMER ARL6IP1 Antibody (Catalog # A08487). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

ARMER antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ARMER ARL6IP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08487)

Host

Rabbit

Contents

ARMER Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER. The immunogen is located within the last 50 amino acids of ARMER.

Reactive Species

A08487 is reactive to ARL6IP1 in Human, Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

23.4 kDa

Background of ARL6IP1

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08487 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ARMER antibody can be used for detection of ARMER by Western blot at 0.5 to 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 2 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information ARL6IP1

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