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Product Info Summary
| SKU: | A11053 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-ATG2B Antibody
SKU/Catalog Number
A11053
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ATG2B Antibody (Catalog # A11053). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
ATG2B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ATG2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11053)
Host
Rabbit
Contents
ATG2B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
ATG2B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATG2B. The immunogen is located within amino acids 450 - 500 of ATG2B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ATG2B antibody is predicted to not cross-react with other ATG2A.
Reactive Species
A11053 is reactive to ATG2B in Human
Applications
A11053 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
232.763kDa
Background of ATG2B
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ATG2B antibody can be used for detection of ATG2B by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ATG2B in K562 cell lysate with ATG2B antibody at (A) 1 and (B) 2 μg/ml
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Immunofluorescence of ATG2B in K562 cells with ATG2B antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ATG2B (Source: Uniprot.org, NCBI)
Gene Name
ATG2B
Full Name
Autophagy-related protein 2 homolog B
Weight
232.763kDa
Superfamily
ATG2 family
Alternative Names
ATG2 autophagy related 2 homolog B (S. cerevisiae); C14orf103; FLJ10242 ATG2B C14orf103 autophagy related 2B autophagy-related protein 2 homolog B|ATG2 autophagy related 2 homolog B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ATG2B, check out the ATG2B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ATG2B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ATG2B Antibody (A11053)
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No publications found for A11053
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