Anti-Atrophin-1 ATN1 Antibody

Product Name

Anti-Atrophin-1 ATN1 Antibody

View all ATN1 Antibodies

SKU/Catalog Number

A03828-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Atrophin-1 ATN1 Antibody catalog # A03828-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Atrophin-1 ATN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03828-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human Atrophin-1. at AA rangle: 50-130

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03828-1 is reactive to ATN1 in Human, Mouse, Rat

Applications

A03828-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

125.414kDa

Background of ATN1

Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
ELISA 1:5000

Validation Images & Assay Conditions

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Western blot analysis of various cells using Atrophin-1 Polyclonal Antibody

Gene/Protein Information For ATN1 (Source: Uniprot.org, NCBI)

Alternative Names

ATN1; atrophin 1; atrophin-1; B37; D12S755E; dentatorubral-pallidoluysian atrophy (atrophin-1); Dentatorubral-pallidoluysian atrophy protein; DRPLA; DRPLANOD; HRS; NOD ATN1 B37, CHEDDA, D12S755E, DRPLA, HRS, NOD atrophin 1 atrophin-1|dentatorubral-pallidoluysian atrophy protein

For more info on ATN1, check out the ATN1 Infographic

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In this infographic, you will see the following information for ATN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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