Product Info Summary
SKU: | PA2248 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Vasopressin V1a receptor AVPR1A Antibody
View all V1a Vasopressin R/AVPR1A Antibodies
SKU/Catalog Number
PA2248
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Vasopressin V1a receptor AVPR1A Antibody catalog # PA2248. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Vasopressin V1a receptor AVPR1A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2248)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A, different from the related human and mouse sequences by one amino acid.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2248 is reactive to AVPR1A in Human, Mouse, Rat
Applications
PA2248 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
47 kDa
Calculated molecular weight
46.8kDa
Background of V1a Vasopressin R/AVPR1A
Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Validation Images & Assay Conditions
Click image to see more details
Anti-AVPR1A antibody, PA2248, All Western blotting
All lanes: Anti-AVPR1A(PA2248) at 0.5ug/ml
Lane 1: Rat Liver Tissue Lysate at 40ug
Lane 2: Rat Kidney Tissue Lysate at 40ug
Predicted bind size: 47KD
Observed bind size: 47KD
Protein Target Info & Infographic
Gene/Protein Information For AVPR1A (Source: Uniprot.org, NCBI)
Gene Name
AVPR1A
Full Name
Vasopressin V1a receptor
Weight
46.8kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
Antidiuretic hormone receptor 1a; arginine vasopressin receptor 1A; AVPR V1a; AVPR1; AVPR1A; SCCL vasopressin subtype 1a receptor; V1a Vasopressin R; V1a vasopressin receptor; V1a VasopressinR; V1aR; V1-vascular vasopressin receptor AVPR1A; Vascular/hepatic-type arginine vasopressin receptor; vasopressin V1a receptor AVPR1A AVPR V1a, AVPR1, V1aR arginine vasopressin receptor 1A vasopressin V1a receptor|SCCL vasopressin subtype 1a receptor|V1-vascular vasopressin receptor AVPR1A|V1a vasopressin receptor|antidiuretic hormone receptor 1A|vascular/hepatic-type arginine vasopressin receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AVPR1A, check out the AVPR1A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AVPR1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Vasopressin V1a receptor AVPR1A Antibody (PA2248)
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No publications found for PA2248
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-Vasopressin V1a receptor AVPR1A Antibody
Question
We are currently using anti-AVPR1A antibody PA2248 for mouse tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on bovine tissues as well?
Verified Customer
Verified customer
Asked: 2018-05-28
Answer
The anti-AVPR1A antibody (PA2248) has not been tested for cross reactivity specifically with bovine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2018-05-28