Product Info Summary
SKU: | A07380 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-Bcl-B BCL2L10 Antibody
SKU/Catalog Number
A07380
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Bcl-B BCL2L10 Antibody (Catalog # A07380). Tested in ELISA, WB, ICC applications. This antibody reacts with Human.
Storage & Handling
Bcl-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Bcl-B BCL2L10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07380)
Host
Rabbit
Contents
Bcl-B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Bcl-B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human Bcl-B. The immunogen is located within amino acids 90 - 140 of Bcl-B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
LANCL2 antibody is human, mouse and rat reactive.
Reactive Species
A07380 is reactive to BCL2L10 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
21973 MW
Background of BCL2L10
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07380 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Bcl-B antibody can be used for the detection of Bcl-B by Western blot at 1 - 2 μg/mL. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of Bcl-B in Jurkat cell lysate with Bcl-B antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For BCL2L10 (Source: Uniprot.org, NCBI)
Gene Name
BCL2L10
Full Name
Bcl-2-like protein 10
Weight
21973 MW
Superfamily
Bcl-2 family
Alternative Names
Boo, Diva, BCL-B, BCLB, Bcl-2-like protein 10, Anti-apoptotic protein NrH, Bcl2-L-10 BCL2L10 BCL-B, Boo, Diva, bcl2-L-10 BCL2 like 10 bcl-2-like protein 10|BCL2-like 10 (apoptosis facilitator)|anti-apoptotic protein NrH|apoptosis regulator Bcl-B|death inducer binding to vBcl-2 and Apaf-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BCL2L10, check out the BCL2L10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BCL2L10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Bcl-B BCL2L10 Antibody (A07380)
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