Anti-BDH1 Monoclonal Antibody

Product Name

Anti-BDH1 Monoclonal Antibody

View all BDH1 Antibodies

SKU/Catalog Number

A09277

Size

100μl

Form

Liquid

Description

Boster Bio Anti-BDH1 Monoclonal Antibody catalog # A09277. Tested in IHC, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-BDH1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09277)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

1A5

Isotype

IgG

Immunogen

Purified recombinant fragment of human BDH1 expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A09277 is reactive to BDH1 in Human, Mouse

Applications

A09277 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

38.157kDa

Background of BDH1

APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
IHC, 1:200-1:1000

Validation Images & Assay Conditions

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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Liver cancer (left) and colorectal cancer tissues (right) with DAB staining using BDH1 Monoclonal antibody.

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Western Blot (WB) analysis using BDH1 Monoclonal antibody against HepG2 (1) and NIH/3T3 (2) cell lysate.

Gene/Protein Information For BDH1 (Source: Uniprot.org, NCBI)

Alternative Names

(R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase, type 1; EC 1.1.1; MGC2723; MGC4347; MGC9788; mitochondrial; mitochondrial); short chain dehydrogenase/reductase family 9C, member 1 BDH1 BDH, SDR9C1 3-hydroxybutyrate dehydrogenase 1 D-beta-hydroxybutyrate dehydrogenase, mitochondrial|(R)-3-hydroxybutyrate dehydrogenase|3-hydroxybutyrate dehydrogenase (heart, mitochondrial)|3-hydroxybutyrate dehydrogenase, type 1|epididymis secretory sperm binding protein|short chain dehydrogenase/reductase family 9C member 1

For more info on BDH1, check out the BDH1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BDH1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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