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- Table of Contents
BECN1P1 antibody (A12290) performs well in ELISA, IF, IHC-P, WB and shows reactivity with Human.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunofluorescence of Beclin 2 in human lung carcinoma tissue with Beclin 2 antibody at 20 μg/ml.
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Anti-Beclin 2 BECN2 Antibody
BECN1P1 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human | Rabbit | ELISA, IF, IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
Beclin 2 antibody can be used for detection of Beclin 2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Beclin 2 BECN2 Antibody
View all BECN1P1 Antibodies
View all BECN1P1 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
Beclin 2 antibody can be stored at 4°C, stable for up to one year.
Host
Rabbit
Contents
Beclin 2 antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Beclin 2 antibody was raised against a 16 amino acid peptide near the amino terminus of human Beclin 2. The immunogen is located within amino acids 30 - 80 of Beclin 2.
Cross-Reactivity
Beclin 2 antibody is human specific. At least two isoforms of Beclin 2 are known to exist; this antibody will only detect the longer isoform. Beclin 2 antibody is predicted to not cross-react with Beclin 1.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
48.2 kDa
Background of BECN1P1
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin 2 is a mammalian specific homolog of the autophagy protein Beclin 1 (3). Like Beclin 1, Beclin 2 interacts with Bcl-2 and class III PI3K complex components. However, Beclin 2 functions in an additional lysosomal degradation pathway and is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (3). Beclin 2 is also required for agonist-induced lysosome-mediated degradation of EGFR in lung cancer cells, suggesting that it may also play a role in regulating other intracellular signaling pathways (4).
Cite This Product
Anti-Beclin 2 BECN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12290)
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Product Promise
We promise Anti-Beclin 2 BECN2 Antibody performs excellently in relevant applications for ELISA, IF, IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
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A12290
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 1, 2026