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Actb antibody (M01263-9) performs well in IHC, WB and shows reactivity with Chicken, Human, Monkey, Mouse, Pig, Rabbit, Rat.

Validated for inter-lot consistency, specificity, and reproducibility
Committed to quality since 1993
Over 65 Publications

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Anti-Beta-Actin Actb Antibody (Monoclonal, 31A06)

Actb antibody

65 Publications

Reactive Species	Host	Application
Chicken, Human, Monkey, Mouse, Pig, Rabbit, Rat	Mouse	IHC, WB

Product Information

Product Name

Anti-Beta-Actin Actb Antibody (Monoclonal, 31A06)
View all ACTB Antibodies

Form

Lyophilized

Uniprot

P60711

Gene ID

81822

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Host

Mouse

Contents

Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Monoclonal

Clone Number

31A06

Isotype

Mouse IgG1

Immunogen

slightly modified beta-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.

Cross-Reactivity

No cross-reactivity with other proteins

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Calculated Molecular Weight

41.7 kDa

Background of Actb

The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al. (1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.

Cite This Product

Anti-Beta-Actin Actb Antibody (Monoclonal, 31A06) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01263-9)

Publications

Cordycepin inhibits pancreatic cancer progression and enhances gemcitabine sensitivity by targeting the CDK2/E2F2 axis to modulate TNNI2 expression

Published: 2026-07-29

Journal: BIOCHEMICAL PHARMACOLOGY

Application: WB

Impact Factor: 6.50

Species: Human

PMID: 42526773

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Free Secondary Antibody

Anti-Beta-Actin Actb Antibody (Monoclonal, 31A06)

Actb antibody

Overview

Recommend Dilution

Product Information

Publications

Cordycepin inhibits pancreatic cancer progression and enhances gemcitabine sensitivity by targeting the CDK2/E2F2 axis to modulate TNNI2 expression

SSO targets CD36 to regulate lipid metabolism disorders and improve SiO2 induced fibrosis

MiR-92a-3p aggravates myocardial injury and cardiac dysfunction in septic cardiomyopathy by inhibiting Dusp1

Myeloid-Derived Growth Factor Improves Endothelial Progenitor Cell Function and Angiogenesis in Mice With Diabetic Hindlimb Ischemia by Activating Akt/HIF-1α Signalling Pathway

Lipoprotein (a) fuels EV71 replication by activating p38 MAPK-autophagy axis

Ultrasound-responsive nanodroplets activate the Hippo pathway via ROS-MST1-YAP cascade for breast cancer therapy

Neuregulin 4 improves white adipose tissue inflammation in mice with polycystic ovary syndrome

TRIM21 inhibited PRV infection and downregulated IFN-α, IL-6, and TNF-α during the infection

ACE2 ameliorates DOX-induced cardiotoxicity by suppressing excessive autophagy via the AMPK/mTOR signaling pathway

High intensity 40 Hz flicker improves amyloid pathology and cognition with autophagy in 3xTg mice

Pyruvate carboxylase promotes SREBP1a-mediated lipid synthesis in epithelial ovarian cancer

Amyloid Precursor Protein Abnormalities Destabilize Membrane Ferroportin: A Novel Mechanism Underlying Early Brain Pathologies and Memory Impairment in Alzheimer’s Disease

PIP2 Accumulation in the Spongiotrophoblast Drives Trophoblast Apoptosis in Intrahepatic Cholestasis of Pregnancy

FATP4 Switches Cellular Lipid Utilization via the PI3K-AKT Pathway in Goat Preadipocytes

Atractylenolide III improves ovarian dysfunction and endometrial receptivity in a PCOS rat model by regulating Cybb-mediated oxidative stress

Network toxicology and machine learning revealed the association between non-alcoholic fatty liver disease induced by polystyrene nanoplastics

Antimicrobial Peptide pBD2 Alleviates Intestinal Damage by Regulating MAPK and Nrf2 Signaling Pathway and Intestinal Microbiota in Mice Challenged with Enterotoxigenic Escherichia Coli K88

BPGM as an intrinsic brake to constrain metastasis through phospho-epigenetic-mediated carnitine biosynthesis suppression

BEZ235 enhances the photodynamic antitumor efficacy of hypoxia-responsive BODIPY prodrug nanoparticles by inhibiting the PI3K/mTOR pathway and alleviating hypoxia

Antibacterial effects of epigallocatechin gallate against calf diarrhea-causing Escherichia coli: in vitro and in vivo investigations

IL-1β neutralization ameliorates cognitive deficits and tau pathology in a mouse model of Alzheimer's disease with hyperhomocysteinemia

Aptamer-Functionalized Exosomes Combined with Doxorubicin Suppress GBM Progression and Enhance Chemoradiosensitivity by Promoting Pyroptosis

Design, Synthesis, and Investigation of Anti-liver Fibrosis Activity of Steroidal VDR Modulators via Side-Chain Modifications

Resveratrol attenuates high-fat diet-induced testicular injury via the NRF2/GPX4 pathway: an integrated metabolomics and network pharmacology study

GRHL2/SENP1/VDR Signaling Axis: A Key Regulator of SUMOylation and Calcitriol Resistance in SHPT

Retigabine ameliorates CRS-induced depressive-like behaviors and cognitive impairment by inhibiting endoplasmic reticulum stress-mediated apoptosis

miR-16-5p Attenuated Airway Inflammation and Pulmonary Fibrosis of Asthma Rats by Regulating the TGF-β1/Smad3 Signaling

TrpC5 silencing reduces cell invasion and migration and enhances radiosensitivity in papillary thyroid carcinoma cells

Targeting the FAPα/Integrin αvβ1 complex attenuates hepatic stellate cell activation and liver fibrosis

Immunoprotective potential of steamed Panax notoginseng saponins: chemical characterization and mechanistic insights via the TLRs/NF-κB pathway

Unveiling the protective mechanisms of Pipa Qingfei Decoction in pulmonary arterial hypertension: Insights from network pharmacology, metabolomics and Mendelian randomization

Electroacupuncture pretreatment regulates mitophagy in ULK1 knockout mice subjected to cerebral ischemia-reperfusion injury

TANK-binding Kinase 1 regulates the intracellular survival of Brucella

Probiotic and antibacterial properties of recombinant Lactococcus lactis expressing the fusion antimicrobial peptides BMAP18-BSN37 in mice and chickens

Effects of intermittent hypoxia on adipose-derived mesenchymal stem cells in protecting alveolar type II cells from injury

Daucosterol Targets PFKFB3 to Mitigates Sepsis-Induced Acute Lung Injury by Inhibiting Glycolysis and M1 Macrophage Polarization

Novel insights into the regulation of NF2/SWH signaling in granulosa cells of prehierarchical follicle development in hen ovary

Gu-Jin-Xiao-Ji Decoction potentiates anti-PD-1 immunotherapy in lung cancer by inhibiting the PI3K/AKT/NF-κB/PD-L1 axis

A self-amplifying cuproptosis nanomedicine to overcome immunosuppression by blocking tumor-derived exosomes for enhancing lung cancer immunotherapy

AARS1-mediated AKR1B10 lactylation stabilizes an aerobic glycolysis-positive feedback loop to drive lenvatinib resistance in hepatocellular carcinoma

Astaxanthin inhibits the aggregation and cytotoxicity of tau4RDΔK280 via possible interaction with the aggregation-prone segments

Modulation of endothelial-to-mesenchymal transition via NRP-1 targeting with melittin attenuates pulmonary fibrosis

Identification of potential molecular targets of rhaponticin in the treatment of periodontitis using bioinformatics tools

Integrated analysis of RNA-binding proteins in MAFLD: mechanistic insights and diagnostic biomarker potential via alternative splicing

Neuronal differentiation regulator CEND1 coordinately suppresses tumor growth and energetics via AMPK signaling in brain glioma

Water-soluble polysaccharides from citri reticulatae pericarpium alleviates LCWE-induced endothelial dysfunction by targeting TLR2-mediated NF-κB-NLRP3 pathway

Impaired Gq signaling underlies oxytocin hyporesponsiveness in LPS and poly I:C-induced preterm labor in mice

Inhibiting HSCs Activation and Ameliorating Alcoholic Liver Fibrosis by Fucoidan Targeting the TLR4/NF-κB Pathway

PLIN5 Promotes Lipid Reconstitution in Goat Intramuscular Fat via the PPARγ Signaling Pathway

Cadmium induces ferroptosis in B cells via ATP6V0A1-upregulated lysosomal ferritinophagy: insights from murine transcriptomics and human cellular models

Inhibition of PGK1 ameliorates acute kidney injury through inactivating the PKM2/ALOX12/ferroptosis pathway in a study with male mice

Tailored brain metastatic tumor cells-derived apoptotic bodies ameliorate Alzheimer’s disease by promoting microglia efferocytosis and neuroinflammation mitigation

Chlorella-derived natural photosynthetic system for in situ energy metabolism enhancement in cardiomyocytes

Investigating the role of the ALPK1 signaling pathway in the pathogenesis of diabetic retinopathy

Dietary Supplementation with Selenium Yeast Mitigates Diquat-Induced Oxidative Damage in Oviductal Magnum of Hens

Design, Synthesis, and Evaluation of Antifibrotic Activity of Nonsteroidal VDR Agonists Featuring 1,6-Naphthol as a CD-Ring Surrogate

OGT-mediated O-GlcNAcylation of OR51F2 protein aggravates the malignant phenotypes of prostate cancer cells

Effects of Mume Fructus extract on smoking-induced cough and TNBS-induced colitis in rats and its underlying mechanisms based on gut-lung body fluid metabolism

EphA/EphrinA5 signaling pathway involved in the abnormal synaptic remodeling and neurotoxicity caused by benzo[a]pyrene

Development of Novel Peptide-Based 68Ga-Labeled Radiotracers for Detecting ROR1 Expression in Tumors

Ferulic acid derived from Huanshaodan improves cognitive deficits in Alzheimer's disease model through regulating APP proteolytic processing via downregulation of SIRT2 expression

Dibutyl phthalate promotes COAD cells growth and migration via the TIMP1/PI3K/AKT signaling axis

Sanqi Qushi Formula Ameliorates Podocyte Injury in Membranous Nephropathy by Inhibiting Endoplasmic Reticulum Stress-Induced Ferroptosis

Mitophagy Attenuates Pyroptosis in Human Gingival Fibroblasts through Inhibition of NLRP3 Inflammasome Activation

Monascus Yellow Pigments Ameliorate Hyperuricemia via Dual Mechanisms: Xanthine Oxidase Inhibition and Uric Acid Transporter Modulation (ABCG2, URAT1, and GLUT9)

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