SKU MA1115
Size 100μg/vial
Reactivity Human, Mouse, Rat
Clonality Monoclonal
Clone Number AC-15
Host Mouse
Ig Isotype Mouse IgG1
Applications IHC, WB

Overview

Product Name Anti-Beta-Actin Antibody (Monoclonal, AC-15)
SKU/Catalog Number MA1115
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100μg/vial
Description Mouse IgG monoclonal antibody for beta-Actin, actin, beta (ACTB) detection. Tested with WB, IHC-P in Human;mouse;rat. No cross reactivity with other proteins.
Cite This Product Anti-Beta-Actin Antibody (Monoclonal, AC-15) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1115)
Host Mouse
Contents/Buffer Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Form Lyophilized
Immunogen slightly modified beta-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.
Reactivity Human, Mouse, Rat

Assay Details

Assay Dilutions Overview

Concentration: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Human, mouse, rat, By Heat
Western blot, 0.25-0.5μg/mlμg/ml, Human, mouse, rat

Boster's Secondary Antibodies And IHC, WB Kits

The following reagents are used to generate the images below.

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Images And Assay Conditions

/antibody/ma1115 1 WB anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, Western blotting
Lane 1: Rat Ovary Tissue Lysate
Lane 2: Rat Testis Tissue Lysate
Lane 3: Rat Cardiac Muscle Tissue Lysate
Lane 4: Rat Brain Tissue Lysate
Lane 5: A453 Cell Lysate
Lane 6: HE

/antibody/ma1115 2 WB anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, Western blotting
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Spleen Tissue Lysate
Lane 3: Rat Brain Tissue Lysate
Lane 4: Rat Kidney Tissue Lysate
Lane 5: HELA Cell Lysate
Lane 6: SMMC Cell

/antibody/ma1115 3 IHC anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, IHC(P)
IHC(P): Mouse Intestine Tissue

/antibody/ma1115 4 IHC anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, IHC(P)
IHC(P): Rat Intestine Tissue

/antibody/ma1115 5 IHC anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, IHC(P)
IHC(P): Human Intestinal Cancer Tissue

/antibody/ma1115 6 IHC anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, IHC(P)
IHC(P): Human Lung Cancer Tissue

/antibody/ma1115 7 IHC anti beta actin antibody monoclonal ac 15.jpg

Anti-beta-Actin antibody (monoclonal), MA1115, IHC(P)
IHC(P): Human Mammary Cancer Tissue

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P60711
Gene Name ACTB
Protein Name Actin, cytoplasmic 1
Alternative Names Actin, cytoplasmic 1;Beta-actin;Actin, cytoplasmic 1, N-terminally processed;Actb;
Subcellular Localization Cytoplasm, cytoskeleton. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
Molecular Weight 41737 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Research Areas Actin, Actin Etc, Cytoskeleton, Cytoskeleton / Ecm, Microfilaments, Signal Transduction

*You can search these to find other products in these research areas.
Background The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al.(1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.

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Order Product (MA1115)

Promotion:

Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
Option Price
30ug sample size $99
100ug $280
100ug+Free HRP Secondary BA1050 $280
100ug+Free Biotin Secondary BA1001 $280

USD $280

Ships next business day.

Troubleshooting

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Publications

Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning
Lead poisoning disturbs oligodendrocytes differentiation involved in decreased expression of NCX3 inducing intracellular calcium overload
Oxymatrine ameliorates doxorubicin-induced cardiotoxicity in rats
Exogenous %u03B1-calcitonin gene-related peptide attenuates lipopolysaccharide-induced acute lung injury in rats
Inhibition of cardiomyocytes hypertrophy by resveratrol is associated with amelioration of endoplasmic reticulum stress
Curcumin regulates the metabolism of low density lipoproteins by improving the C-to-U RNA editing efficiency of apolipoprotein B in primary rat hepatocytes
Astaxanthin reduces type 2 diabetic%u2011associated cognitive decline in rats via activation of PI3K/Akt and attenuation of oxidative stress
Calcimimetic R568 reduced the blood pressure and improved aortic remodeling in spontaneously hypertensive rats by inhibiting local renin%u2011angiotensin system %u2026
Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/%u03B2-catenin pathway
Polyamine depletion attenuates isoproterenol-induced hypertrophy and endoplasmic reticulum stress in cardiomyocytes
Decreased expression of transforming growth factor-%u03B21 and %u03B1-smooth muscle actin contributes to the protection of lotensin against chronic renal failure in rats
Resistance of interleukin-6 to the extracellular inhibitory environment promotes axonal regeneration and functional recovery following spinal cord injury
Effects of caffeic acid on learning deficits in a model of Alzheimer's disease
Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1 %u2026
Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1 %u2026
Expression of TLR2/4 on Epididymal Spermatozoa of the Chinese Soft%u2010Shelled Turtle Pelodiscus sinensis During the Hibernation Season
Alleviation of mycotoxin biodegradation agent on zearalenone and deoxynivalenol toxicosis in immature gilts
Crosstalk between endoplasmic reticulum stress and mitochondrial pathway mediates cadmium-induced germ cell apoptosis in testes
Weanling Offspring of Dams Maintained on Serine-Deficient Diet Are Vulnerable to Oxidative Stress
Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo
Effects of aqueous extracts of Taraxacum Officinale on expression of tumor necrosis factor-alpha and intracellular adhesion molecule 1 in LPS-stimulated %u2026
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets
RETRACTED: Transcription factor activator protein%u20102%u03B2 accelerates lipid accumulation in macrophages via enhancing the transcription of CD36
Dipeptide (Methionyl-Methionine) transport and its effect on %u03B2-Casein synthesis in bovine mammary epithelial cells
The zebrafish miR-125c is induced under hypoxic stress via hypoxia-inducible factor 1%u03B1 and functions in cellular adaptations and embryogenesis
miR-21 Reduces Hydrogen Peroxide-Induced Apoptosis in c-kit
miR-21 increases c-kit cardiac stem cell proliferation in vitro through PTEN/PI3K/Akt signaling
Polydatin attenuates diet-induced nonalcoholic steatohepatitis and fibrosis in mice
Efficacy of acetylshikonin in preventing obesity and hepatic steatosis in db/db mice
Cytoprotective role of alpha-1 antitrypsin in vascular endothelial cell under hypoxia/reoxygenation condition
Fucoidan inhibits angiogenesis induced by multiple myeloma cells
MiR-665 aggravates heart failure via suppressing CD34-mediated coronary microvessel angiogenesis
Herpes simplex virus type 1 VP22-mediated intercellular delivery of PTEN increases the antitumor activity of PTEN in esophageal squamous cell carcinoma %u2026
Anti-inflammatory effect of the blueberry anthocyanins malvidin-3-glucoside and malvidin-3-galactoside in endothelial cells
Deguelin Attenuates Allergic Airway Inflammation via Inhibition of NF-%u03BAb Pathway in Mice
Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-%u03BAB pathway
Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer
Cryptolepine derivative-6h inhibits liver fibrosis in TGF-%u03B21-induced HSC-T6 cells by targeting the Shh pathway
Effects of integrin %u03B1%u03BD%u03B23 on differentiation and collagen synthesis induced by connective tissue growth factor in human hypertrophic scar fibroblasts
Identification of serum %u03B2-catenin as a biomarker in patients with HBV-related liver diseases
Caveolin%u20111 facilitated KCNA5 expression, promoting breast cancer viability
Autophagy in human skin squamous cell carcinoma: Inhibition by 3-MA enhances the effect of 5-FU-induced chemotherapy sensitivity
miR-146b-5p functions as a tumor suppressor by targeting TRAF6 and predicts the prognosis of human gliomas
Cullin1 is a novel marker of poor prognosis and a potential therapeutic target in human breast cancer
Pro-apoptotic effects of tectorigenin on human hepatocellular carcinoma HepG2 cells
N-methyl-D-aspartate Receptors Mediate Epilepsy-Induced Axonal Impairment and Tau Phosphorylation via Activating Glycogen Synthase Kinase-3%u03B2 and %u2026
ER stress contributes to alpha-naphthyl isothiocyanate-induced liver injury with cholestasis in mice
Nuclear Drosha enhances cell invasion via an EGFR-ERK1/2-MMP7 signaling pathway induced by dysregulated miRNA-622/197 and their targets LAMC2 %u2026
Ursolic acid alleviates early brain injury after experimental subarachnoid hemorrhage by suppressing TLR4-mediated inflammatory pathway
Copper ion attenuated the antiproliferative activity of di-2-pyridylhydrazone dithiocarbamate derivative; however, there was a lack of correlation between ROS %u2026
LY294002 induces G0/G1 cell cycle arrest and apoptosis of cancer stem-like cells from human osteosarcoma via down-regulation of PI3K activity
Downregulation of mitochondrial cyclooxygenase-2 inhibits the stemness of nasopharyngeal carcinoma by decreasing the activity of dynamin-related protein %u2026
Synergistic effect of TRAIL and irradiation in elimination of glioblastoma stem-like cells
Dicer affects cisplatin%u2011mediated apoptosis in epithelial ovarian cancer cells
Epigenetic regulation of miR%u2010124 by hepatitis C virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3
Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism
Inhibition of cpu0213, a dual endothelin receptor antagonist, on apoptosis via nox4-dependent ros in hk-2 cells
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-%u03BAB Signaling Pathway
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-%u03BAB Signaling Pathway
Blocking FGFR4 exerts distinct anti%u2010tumorigenic effects in esophageal squamous cell carcinoma
mir-361-5p inhibits glioma migration and invasion by targeting snD1
NDRG2 promotes adriamycin sensitivity through a Bad/p53 complex at the mitochondria in breast cancer
NDRG2 expression regulates CD24 and metastatic potential of breast cancer cells
Flap endonuclease 1 silencing is associated with increasing the cisplatin sensitivity of SGC%u20117901 gastric cancer cells
Oxymatrine Inhibits Homocysteine-Mediated Autophagy via MIF/mTOR Signaling in Human Umbilical Vein Endothelial Cells
miR-153 inhibits epithelial-to-mesenchymal transition in hepatocellular carcinoma by targeting Snail
Metformin enhances the chemosensitivity of hepatocarcinoma cells to cisplatin through AMPK pathway
The effects of demecolcine, alone or in combination with sucrose on bovine oocyte protrusion rate, MAPK1 protein level and c-mos gene expression level
Streptococcus suis synthesizes deoxyadenosine and adenosine by 5'-nucleotidase to dampen host immune responses
Clematichinenoside (AR) attenuates hypoxia/reoxygenation-induced H9c2 cardiomyocyte apoptosis via a mitochondria-mediated signaling pathway
HSP90 regulates larval settlement of the bryozoan Bugula neritina through the nitric oxide pathway
LZ-207, a Newly Synthesized Flavonoid, Induces Apoptosis and Suppresses Inflammation-Related Colon Cancer by Inhibiting the NF-?B Signaling Pathway
Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-?B mediated matrix metalloproteinase-1 gene regulation
Roles of mitochondrial transcription factor A and microRNA-590-3p in the development of colon cancer
Paeoniflorin reduced BLP-induced inflammatory response by inhibiting the NF-?B signal transduction in pathway THP-1 cells
N-acetylcysteine reduces oxidative stress, nuclear factor-?B activity and cardiomyocyte apoptosis in heart failure
HIF-1? Inhibition Reduces Nasal Inflammation in a Murine Allergic Rhinitis Model
Effects of hypoxia-inducible factor-1? and matrix metalloproteinase-9 on alveolar-capillary barrier disruption and lung edema in rat models of severe acute pancreatitis-associated lung injury
Ailanthone induces G2/M cell cycle arrest and apoptosis of SGC-7901 human gastric cancer cells
MicroRNA-125b Promotes Hepatic Stellate Cell Activation and Liver Fibrosis by Activating RhoA Signaling
Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone
Expression of p53 and its mechanism in prostate cancer
Application of Ferulic Acid for Alzheimer?s Disease: Combination of Text Mining and Experimental Validation
CaMKII Activation Promotes Cardiac Electrical Remodeling and Increases the Susceptibility to Arrhythmia Induction in High-fat Diet?Fed Mice With Hyperlipidemia Conditions
Effects of hepatitis E virus infection on interferon production via ISG15
Expression of Caspase-1 in breast cancer tissues and its effects on cell proliferation, apoptosis and invasion
Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts
MicroRNA-155 increases colon cancer chemoresistance to cisplatin by targeting forkhead box O3
Expression and function of tetraspanin 1 in esophageal carcinoma
MiR-29b/TET1/ZEB2 signaling axis regulates metastatic properties and epithelial-mesenchymal transition in breast cancer cells
NDRG4 promotes myogenesis via Akt/CREB activation
Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter
Mesenchymal stem cells overexpressing adrenomedullin improve heart function through antifibrotic action in rats experiencing heart failure
Epigallocatechin-3-gallate induces apoptosis in acute promyelocytic leukemia cells via a SHP-1-p38? MAPK-Bax cascade
Mesenchymal stromal cells ameliorate oxidative stress-induced islet endothelium apoptosis and functional impairment via Wnt4-?-catenin signaling
Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor ? co-activator-1? protein
F10, a novel hydatidiform mole-associated gene, inhibits the paclitaxel sensitivity of A549 lung cancer cells by downregulating BAX and caspase-3
Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm
STAT3 and NF-?B are Simultaneously Suppressed in Dendritic Cells in Lung Cancer
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells
BDNF/TRK/KCC2 pathway in nicotine withdrawal-induced hyperalgesia
A neutralized human LMP1-IgG inhibits ENKTL growth by suppressing the JAK3/STAT3 signaling pathway
The overexpressed functional transient receptor potential channel TRPM2 in oral squamous cell carcinoma
Rifampicin Attenuated Global Cerebral Ischemia Injury via Activating the Nuclear Factor Erythroid 2-Related Factor Pathway
Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication
Anti-tumor effects of Abnormal Savda Munziq on the transplanted cervical cancer (U27) mouse model
NLS-RAR? modulates acute promyelocytic leukemia NB4 cell proliferation and differentiation via the PI3K/AKT pathway
Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism
Generation of V ?13/?21+T cell specific target CML cells by TCR gene transfer
miR-448 downregulates MPPED2 to promote cancer proliferation and inhibit apoptosis in oral squamouscellcarcinoma
MicroRNA-552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28
C5a Induces the Synthesis of IL-6 and TNF-? in Rat Glomerular Mesangial Cells through MAPK Signaling Pathways
The Hippo/MST Pathway Member SAV1 Plays a Suppressive Role in Development of the Prehierarchical Follicles in Hen Ovary
The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth
RIG-I inhibits pancreatic ? cell proliferation through competitive binding of activated Src
Expression of hyperpolarization-activated cyclic nucleotide-gated channel isoforms in a canine model of atrial fibrillation
Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling
Tubeimoside-1 induces oxidative stress-mediated apoptosis and G0/G1 phase arrest in human prostate carcinoma cells in vitro
ROCK2 mediates the proliferation of pulmonary arterial endothelial cells induced by hypoxia in the development of pulmonary arterial hypertension
NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells
Stathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cells
Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats
N-n-butyl haloperidol iodide ameliorates hypoxia/reoxygenation injury through modulating the LKB1/AMPK/ROS pathway in cardiac microvascular endothelial cells
Target delivery of small interfering RNAs with vitamin E-coupled nanoparticles for treating hepatitis C
Retinoic acid-incorporated glycol chitosan nanoparticles inhibit the expression of Ezh2 in U118 and U138 human glioma cells
Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53
YB-1, a new biomarker of glioma progression, is associated with the prognosis of glioma patients
ClC-3 chloride channel in hippocampal neuronal apoptosis
HYOU1, Regulated by LPLUNC1, Is Up-Regulated in Nasopharyngeal Carcinoma and Associated with Poor Prognosis
AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-?1-triggered epithelial-mesenchymal transition
BRG1 Is a Prognostic Marker and Potential Therapeutic Target in Human Breast Cancer
Loss of GATA5 expression due to gene promoter methylation induces growth and colony formation of hepatocellular carcinoma cells.
Effect of CPU-XT-008, a combretastatin A-4 analogue, on the proliferation, apoptosis and expression of vascular endothelial growth factor and basic fibroblast growth factor in human umbilical vein endothelial cells
miR-139 Functions as An Antioncomir to Repress Glioma Progression Through Targeting IGF-1 R, AMY-1, and PGC-1?
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma
NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/?-catenin signaling pathway
Effects of As2O3nanoparticles on cell growth and apoptosis of NB4 cells
Epigenetic Repression of miR-218 Promotes Esophageal Carcinogenesis by Targeting ROBO1
The Functional SNPs in the 5? Regulatory Region of the Porcine PPARD Gene Have Significant Association with Fat Deposition Traits
?-Mannosidase I Protein Expression in Peripheral Blood Mononuclear Cells Is Upregulated During Hepatitis B Virus Infection
Cooperative Effects of FOXL2 with the Members of TGF-? Superfamily on FSH Receptor mRNA Expression and Granulosa Cell Proliferation from Hen Prehierarchical Follicles
HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products
EGR1 regulates hepatic clock gene amplitude by activatingPer1transcription
microRNA-214 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting the suppressor-of-fused protein (Sufu)
miR-200c inhibits breast cancer proliferation by targeting KRAS
N-n-butyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy
MCI extraction from Turkish galls played protective roles against X-ray-induced damage in AHH-1 cells
Ube2s regulates Sox2 stability and mouse ES cell maintenance.
Loss of MiR-664 Expression Enhances Cutaneous Malignant Melanoma Proliferation by Upregulating PLP2
Astaxanthin improves cognitive deficits from oxidative stress, nitric oxide synthase and inflammation through upregulation of PI3K/Akt in diabetes rat.
Rap2B promotes migration and invasion of human suprarenal epithelioma
Hydrogen sulfide accelerates wound healing in diabetic rats
Crocin attenuates lipopolysacchride-induced acute lung injury in mice
EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer
Downregulation of the expression of inhibin ? subunit and betaglycan in porcine cystic follicles
EGCG regulates the cross-talk between JWA and topoisomerase II? in non-small-cell lung cancer (NSCLC) cells
Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood-brain barrier disruption in rabbits.
Ulinastatin suppresses endoplasmic reticulum stress and apoptosis in the hippocampus of rats with acute paraquat poisoning
Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma
CD133+ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition
Incomplete Radiofrequency Ablation Enhances Invasiveness and Metastasis of Residual Cancer of Hepatocellular Carcinoma Cell HCCLM3 via Activating ?-Catenin Signaling
Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma
miRNA-183 Suppresses Apoptosis and Promotes Proliferation in Esophageal Cancer by Targeting PDCD4
Unchanged survival rates of Shadoo knockout mice after infection with mouse-adapted scrapie
Transportation of Berberine into HepG2, HeLa and SY5Y Cells: A Correlation to Its Anti-Cancer Effect
Diallyl Disulfide Suppresses SRC/Ras/ERK Signaling-Mediated Proliferation and Metastasis in Human Breast Cancer by Up-Regulating miR-34a
Heat shock protein 72 suppresses apoptosis by increasing the stability of X-linked inhibitor of apoptosis protein in renal ischemia/reperfusion injury
Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells
A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells
Effects of Negative Pressure Wound Therapy on Mesenchymal Stem Cells Proliferation and Osteogenic Differentiation in a Fibrin Matrix
Expression Profiling of Exosomal miRNAs Derived from Human Esophageal Cancer Cells by Solexa High-Throughput Sequencing
MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R
PELP1 Suppression Inhibits Colorectal Cancer through c-Src Downregulation
Manumycin induces apoptosis in prostate cancer cells
MicroRNA-26b inhibits epithelial-mesenchymal transition in hepatocellular carcinoma by targeting USP9X
Wogonin prevents lipopolysaccharide-induced acute lung injury and inflammation in mice via peroxisome proliferator-activated receptor gamma-mediated attenuation of the nuclear factor-kappaB pathway
Tea polyphenols induced apoptosis of breast cancer cells by suppressing the expression of Survivin
Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma
MicroRNA-26b suppresses the NF-?B signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3
Folic Acid Protects against Lipopolysaccharide-Induced Preterm Delivery and Intrauterine Growth Restriction through Its Anti-Inflammatory Effect in Mice
SPATA12 and Its Possible Role in DNA Damage Induced by Ultraviolet-C
The ClC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis
Combination of Low Concentration of (?)-Epigallocatechin Gallate (EGCG) and Curcumin Strongly Suppresses the Growth of Non-Small Cell Lung Cancer in Vitro and in Vivo through Causing Cell Cycle Arrest
Hepatitis B virus X protein up-regulates tumor necrosis factor-? expression in cultured mesangial cells via ERKs and NF-?B pathways
Regulation Effect of Zinc Fingers and Homeoboxes 2 on Alpha-Fetoprotein in Human Hepatocellular Carcinoma
Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain ?-amyloid through PPAR? activation
Roles of Apolipoprotein E (ApoE) and Inducible Nitric Oxide Synthase (iNOS) in Inflammation and Apoptosis in Preeclampsia Pathogenesis and Progression
Decreased Dicer Expression Enhances SRP-Mediated Protein Targeting
RUNX3 Suppresses Migration, Invasion and Angiogenesis of Human Renal Cell Carcinoma
Inhibition of P-Glycoprotein by HIV Protease Inhibitors Increases Intracellular Accumulation of Berberine in Murine and Human Macrophages
N-acetylcysteine protects against cadmium-induced germ cell apoptosis by inhibiting endoplasmic reticulum stress in testes
PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus
Melatonin Protects against Apoptosis-Inducing Factor (AIF)-Dependent Cell Death during Acetaminophen-Induced Acute Liver Failure
Altered expression levels of IDH2 are involved in the development of colon cancer
Dicer-Dependent Biogenesis of Small RNAs Derived from 7SL RNA
Clara Cell 10-kDa Protein Gene Transfection Inhibits NF-?B Activity in Airway Epithelial Cells
JWA Deficiency Suppresses Dimethylbenz[a]Anthracene-Phorbol Ester Induced Skin Papillomas via Inactivation of MAPK Pathway in Mice
Effect of trimetazidine treatment on the transient outward potassium current of the left ventricular myocytes of rats with streptozotocin-induced type 1 diabetes mellitus
Protein kinase C? downregulation via siRNA-PKC? released from foldable capsular vitreous body in cultured human retinal pigment epithelium cells
The role of SLIT-ROBO signaling in proliferative diabetic retinopathy and retinal pigment epithelial cells
NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression
Role of dopamine D2receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes
Silence of HIN-1 expression through methylation of its gene promoter in gastric cancer
Reduced expression of N-Myc downstream-regulated gene 2 in human thyroid cancer
Generation of diffuse large B cell lymphoma-associated antigen-specific V?6/V?13+T cells by TCR gene transfer
Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats
Phosphatidylinositol 3-kinase affects mitochondrial function in part through inducing peroxisome proliferator-activated receptor ? coactivator-1? expression
The effects of rapamycin on lens epithelial cell proliferation, migration, and matrix formation: An in vitro study
Anti-proliferative and pro-apoptotic effects of tectorigenin on hepatic stellate cells
HSP70: a promising target for laryngeal carcinoma radiaotherapy by inhibiting cleavage and degradation of nucleolin
Acute Stress and Chronic Stress Change Brain-Derived Neurotrophic Factor (BDNF) and Tyrosine Kinase-Coupled Receptor (TrkB) Expression in Both Young and Aged Rat Hippocampus
Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice
Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 mice
HSP72 Inhibits Smad3 Activation and Nuclear Translocation in Renal Epithelial-to-Mesenchymal Transition
Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cells in vitro
Human Immunodeficiency Virus Type 1 Tat Accelerates Kaposi Sarcoma-Associated Herpesvirus Kaposin A-Mediated Tumorigenesis of Transformed Fibroblasts In Vitro as well as in Nude and Immunocompetent Mice
PKC alpha affects cell cycle progression and proliferation in human RPE cells through the downregulation of p27kip1
Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus
Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia
Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors
JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks
Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin
RNAi-mediated inhibition of MSP58 decreases tumour growth, migration and invasion in a human glioma cell line
HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy
Intracellular Tat of Human Immunodeficiency Virus Type 1 Activates Lytic Cycle Replication of Kaposi's Sarcoma-Associated Herpesvirus: Role of JAK/STAT Signaling
Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma
High expression of SLC26A6 in the kidney may contribute to renal calcification via an SLC26A6-dependent mechanism
Expressional and functional interactions of two Apis cerana cerana olfactory receptors
Expression and prognostic value of CLIC1 in epithelial ovarian cancer
Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-?B pathway dependent of HDAC3
SnoN upregulation ameliorates renal fibrosis in diabetic nephropathy
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-?B Signaling Pathway
N-n-butyl Haloperidol Iodide Protects against Hypoxia/Reoxygenation Injury in Cardiac Microvascular Endothelial Cells by Regulating the ROS/MAPK/Egr-1 Pathway
Fermented Chinese Formula Shuan-Tong-Ling Protects Brain Microvascular Endothelial Cells against Oxidative Stress Injury
Epoxyeicosanoids prevent intervertebral disc degeneration?in vitro?and?in vivo
Estrogen-induced SDF-1? production promotes the progression of ER-negative breast cancer via the accumulation of MDSCs in the tumor microenvironment
NEMO-Binding Domain Peptide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting the NF-?B Signaling Pathway
Transplantation of autologous bone marrow mononuclear cells regulates inflammation in a rabbit model of carotid artery atherosclerosis
Monoacylglycerol Lipase: A Novel Potential Therapeutic Target and Prognostic Indicator for Hepatocellular Carcinoma
Positive Feedback Cycle of TNF? Promotes Staphylococcal Enterotoxin B-Induced THP-1 Cell Apoptosis
C1 inhibitor-mediated myocardial protection from chronic intermittent hypoxia-induced injury
miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBP?
The Effects of Aquaporin-1 in Pulmonary Edema Induced by Fat Embolism Syndrome
Slit2?Robo1 signaling promotes the adhesion, invasion and migration of tongue?carcinoma?cellsvia upregulating matrix metalloproteinases 2 and 9, and downregulating E?cadherin
Downregulation of HP1? suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression
MicroRNA-21a-5p Functions on the Regulation of Melanogenesis by Targeting Sox5 in Mouse Skin Melanocytes
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-?B Signaling via TRADD and RIP1
Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury
A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo
Metformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson's Disease via Autophagy and Mitochondrial ROS Clearance
Quantitative Proteomic Analysis of Duck Ovarian Follicles Infected with Duck Tembusu Virus by Label-Free LC-MS
Selective CDK7 inhibition with BS-181 suppresses cell proliferation and induces cell cycle arrest and apoptosis in gastric cancer
Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Properties in Endothelial Cells
Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors
miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway
SENP?1 enhances hypoxia?induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia?inducible factor?1?
Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF-?B Signaling Pathway
Vagus nerve stimulation attenuates myocardial ischemia/reperfusion injury by inhibiting the expression of interleukin-17A
MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes
Argirein alleviates stress-induced and diabetic hypogonadism in rats via normalizing testis endothelin receptor A and connexin 43
The Expression of Porcine Prdx6 Gene Is Up-Regulated by C/EBP? and CREB
Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro
Traditional Chinese medicine Qili qiangxin inhibits cardiomyocyte apoptosis in rats following myocardial infarction
The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway
High glucose induces and activates Toll-like receptor 4 in endothelial cells of diabetic retinopathy
The expansion of autologous adipose-derived stem cells in vitro for the functional reconstruction of nasal mucosal tissue
Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats
Experimental study of the protective effects of SYVN1 against diabetic retinopathy
Lithium chloride attenuates the abnormal osteogenic/adipogenic differentiation of bone marrow-derived mesenchymal stem cells obtained from rats with steroid-related osteonecrosis by activating the ?-catenin pathway
Annexin A5 regulates Leydig cell testosterone production via ERK1/2 pathway
Autologous bone marrow mononuclear cell transplantation delays progression of carotid atherosclerosis in rabbits
Octreotide Protects the Mouse Retina against Ischemic Reperfusion Injury through Regulation of Antioxidation and Activation of NF-?B
Rhizoma Paridis Saponins Suppresses Tumor Growth in a Rat Model of N-Nitrosomethylbenzylamine-Induced Esophageal Cancer by Inhibiting Cyclooxygenases-2 Pathway
MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling
Fructus phyllanthi tannin fraction induces apoptosis and inhibits migration and invasion of human lung squamous carcinoma cells in vitro via MAPK/MMP pathways
Evaluating the Role of PTH in Promotion of Chondrosarcoma Cell Proliferation and Invasion by Inhibiting Primary Cilia Expression
Diagnostic and prognostic value of a disintegrin and metalloproteinase-17 in patients with gliomas
Overexpression of the Survivin gene in SGC7901 cell resistance to cisplatin
Apelin-13 Decreases Lipid Storage in Hypertrophic Adipocytes?In Vitro?Through the Upregulation of AQP7 Expression by the PI3K Signaling Pathway
Preparation and Characterization of a Novel Aspirin Derivative with Anti-Thrombotic and Gastric Mucosal Protection Properties
Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization
Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/?-Catenin Signaling Pathway
The effects of aspirin plus cisplatin on SGC7901/CDDP cells?in vitro
Anti-fibrosis effects of Huisheng oral solution in CCl4-induced hepatic fibrosis in rat
GGPPS1 predicts the biological character of hepatocellular carcinoma in patients with cirrhosis
Function of the transforming growth factor-?1/c-Jun N-terminal kinase signaling pathway in the action of thalidomide on a rat model of pulmonary fibrosis
ERK/CANP rapid signaling mediates 17?-estradiol-induced proliferation of human breast cancer cell line MCF-7 cells
N-n-Butyl Haloperidol Iodide Ameliorates Cardiomyocytes Hypoxia/Reoxygenation Injury by Extracellular Calcium-Dependent and -Independent Mechanisms
VX680 suppresses the growth of HepG2 cells and enhances the chemosensitivity to cisplatin
Hypoxia/oxidative stress alters the pharmacokinetics of CPU86017-RS through mitochondrial dysfunction and NADPH oxidase activation
c?Ski activates cancer?associated fibroblasts to regulate breast cancer cell invasion
Electrospun Poly(L-lactide)/Poly(?-caprolactone) Blend Nanofibrous Scaffold: Characterization and Biocompatibility with Human Adipose-Derived Stem Cells
Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
Sox2 enhances the tumorigenicity and chemoresistance of cancer stem-like cells derived from gastric cancer
Expression profiles of microRNAs from lactating and non-lactating bovine mammary glands and identification of miRNA related to lactation
Combination Therapy with Losartan and Pioglitazone Additively Reduces Renal Oxidative and Nitrative Stress Induced by Chronic High Fat, Sucrose, and Sodium Intake
Overexpression of HTRA1 Leads to Down-Regulation of Fibronectin and Functional Changes in RF/6A Cells and HUVECs
Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells
CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines
Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation by 20(S)-ginsenoside Rh2 in MCF-7/Adr cells
Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 mice
HSP70: a promising target for laryngeal carcinoma radiaotherapy by inhibiting cleavage and degradation of nucleolin
Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors
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Customer Q&As

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: For most of our monoclonal antibodies, we are unable to provide them carrier free. If you would like to check if a specific antibody can be provided carrier free, please send an email to support@bosterbio.com.
Q: What are some alternative names that could be used to describe this product?
A: Some common names include but are not limited to beta-actin antibody, actb antibody, actin beta antibody