Anti-Bile acid receptor NR1H4 Antibody

FXR/NR1H4 antibody

Boster Bio Anti-Bile acid receptor NR1H4 Antibody catalog # A00835. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A00835
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-Bile acid receptor NR1H4 Antibody

View all FXR/NR1H4 Antibodies

SKU/Catalog Number

A00835

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Bile acid receptor NR1H4 Antibody catalog # A00835. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Bile acid receptor NR1H4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00835)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide, corresponding to amino acids 20-70 of Human eEF2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00835 is reactive to NR1H4 in Human, Mouse, Rat

Applications

A00835 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

55.914kDa

Background of FXR/NR1H4

Two elongation factors (EF) EF-Tu and EF-2 participate in the elongation phase during protein biosynthesis on the ribosome and their functional cycles depend on GTP binding and its hydrolysis. EF-Tu (also designated mitochondrial precursor p43) and EF-2 are multidomain GTPases with essential functions in translation, and they both bind to the same site on the ribosome where their low intrinsic GTPase activities are strongly stimulated. EF-Tu plays a central role in the fast and accurate delivery of aminoacyl-tRNAs to the translating ribosome. In addition, EF-Tu protects the aminoester bond against hydrolysis until a correct match between the codon on mRNA and the anticodon on tRNA can be achieved. EF-2 supports the translocation of tRNAs and of mRNAs on the ribosome so that a new codon can be exposed for decoding.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For NR1H4 (Source: Uniprot.org, NCBI)

Gene Name

NR1H4

Full Name

Bile acid receptor

Weight

55.914kDa

Superfamily

nuclear hormone receptor family

Alternative Names

BAR; bile acid receptor; farnesoid X receptor; Farnesoid X-activated receptor; Farnesol receptor HRR-1; FXR; FXRBAR; HRR-1; HRR1MGC163445; NR1H4; Nuclear receptor subfamily 1 group H member 4; nuclear receptor subfamily 1, group H, member 4; Retinoid X receptor-interacting protein 14; RIP14; RIP14RXR-interacting protein 14 NR1H4 BAR, FXR, HRR-1, HRR1, PFIC5, RIP14 nuclear receptor subfamily 1 group H member 4 bile acid receptor|RXR-interacting protein 14|farnesoid X nuclear receptor|farnesoid X-activated receptor|farnesol receptor HRR-1|retinoid X receptor-interacting protein 14

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NR1H4, check out the NR1H4 Infographic

NR1H4 infographic

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In this infographic, you will see the following information for NR1H4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00835-100ul

100ul

$405

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