Anti-BMPR1B Antibody Picoband™

BMPR-IB/ALK-6 antibody

Boster Bio Anti-BMPR1B Antibody Picoband™ catalog # PB9528. Tested in IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: PB9528
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-BMPR1B Antibody Picoband™

View all BMPR-IB/ALK-6 Antibodies

SKU/Catalog Number

PB9528

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-BMPR1B Antibody Picoband™ catalog # PB9528. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-BMPR1B Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9528)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human BMPR1B recombinant protein (Position: K14-Q184). Human BMPR1B shares 97.1% amino acid (aa) sequence identity with mouse BMPR1B.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9528 is reactive to BMPR1B in Human

Applications

PB9528 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

57 kDa

Calculated molecular weight

56.93kDa

Background of BMPR-IB/ALK-6

BMPR1B (Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al. (1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al. (1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For BMPR1B (Source: Uniprot.org, NCBI)

Gene Name

BMPR1B

Full Name

Bone morphogenetic protein receptor type-1B

Weight

56.93kDa

Superfamily

protein kinase superfamily

Alternative Names

activin receptor-like kinase 6; ALK-6; ALK6CDw293; BMP type-1B receptor; BMPR1B; BMPR-1B; BMPRIB; BMPR-IB; bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor, type IB; CDw293 antigen; CDw293; EC 2.7.11; EC 2.7.11.30; serine/threonine receptor kinase BMPR1B ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293 bone morphogenetic protein receptor type 1B bone morphogenetic protein receptor type-1B|BMP type-1B receptor|BMPR-1B|activin receptor-like kinase 6|bone morphogenetic protein receptor, type IB|serine/threonine receptor kinase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BMPR1B, check out the BMPR1B Infographic

BMPR1B infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BMPR1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-BMPR1B Antibody Picoband™

Question

We are currently using anti-BMPR1B antibody PB9528 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on bovine tissues as well?

D. Walker

Verified customer

Asked: 2015-08-13

Answer

The anti-BMPR1B antibody (PB9528) has not been validated for cross reactivity specifically with bovine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2015-08-13

Order DetailsPrice
PB9528

100μg

$370
PB9528-10ug

10μg sample (liquid)

$99
PB9528-Biotin

100 μg Biotin conjugated

$570
PB9528-Cy3

100 μg Cy3 conjugated

$570
PB9528-Dylight488

100 μg Dylight488 conjugated

$570
PB9528-Dylight550

100 μg Dylight550 conjugated

$570
PB9528-Dylight594

100 μg Dylight594 conjugated

$570
PB9528-FITC

100 μg FITC conjugated

$570
PB9528-HRP

100 μg HRP conjugated

$570
PB9528-APC

100 μg APC conjugated

$670
PB9528-PE

100 μg PE conjugated

$670
PB9528-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9528
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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