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Product Info Summary
| SKU: | A04477 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, ICC, WB |
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Product info
Product Name
Anti-C11orf30 EMSY Antibody
SKU/Catalog Number
A04477
Size
100ul
Form
Liquid
Description
Boster Bio Anti-C11orf30 EMSY Antibody catalog # A04477. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-C11orf30 EMSY Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04477)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human SENP3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04477 is reactive to EMSY in Human, Mouse, Rat
Applications
A04477 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
141.468kDa
Background of EMSY
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Yeh E.T.H., Gene 248:1-14(2000).
Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Wiemann S., Genome Res. 11:422-435(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For EMSY (Source: Uniprot.org, NCBI)
Gene Name
EMSY
Full Name
BRCA2-interacting transcriptional repressor EMSY
Weight
141.468kDa
Alternative Names
BRCA2-interacting transcriptional repressor EMSY EMSY C11orf30, GL002 EMSY transcriptional repressor, BRCA2 interacting BRCA2-interacting transcriptional repressor EMSY|EMSY, BRCA2 interacting transcriptional repressor|protein EMSY
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on EMSY, check out the EMSY Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for EMSY: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-C11orf30 EMSY Antibody (A04477)
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No publications found for A04477
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