Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1)
Mouse IgG monoclonal antibody for Calcineurin alpha, protein phosphatase 3, regulatory subunit B, alpha (PPP3R1) detection. Tested with WB, IHC-P in Human;bovine;rat. No cross reactivity with other proteins.
|Reactivity||Bovine, Human, Rat|
|Ig Isotype||Mouse IgG1|
|Product Name||Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1)
See all Ppp3r1 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year, at 4°C for one month. Avoid repeated freezing and thawing.|
|Description||Monoclonal clone# G2 antibody for Calcineurin B/PPP3R1 detection. Host: Mouse.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Bovine. Calcineurin B/PPP3R1 information: Molecular Weight: 19300 MW; Subcellular Localization: Cytoplasm, cytosol . Cell membrane ; Lipid-anchor . Cell membrane, sarcolemma. Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy; Tissue Specificity: Isoform 2 is testis specific.|
|Cite This Product||Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1008)|
|Specificity||Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1) (MA1008) reacts with Bovine, Human, Rat Ppp3r1, in native form and recombinant. Superfamily members of Ppp3r1 are not reactive to MA1008.|
|Contents/Buffer||Each vial contains 50% glycerol, 1.2% Sodium acetate, 1% BSA, 0.02% NaN3.|
|Immunogen||Bovine brain calcineurin.|
|Reactivity||Bovine, Human, Rat|
Our Boster Quality Guarantee for Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1) covers its use in the following applications.
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Assay Dilutions Overview
Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Human, bovine, rat, By Heat
Western blot, 0.25-0.5μg/ml, Human, bovine, rat
Boster's Compatible Products
The following reagents are used to generate the images below for Anti-Calcineurin Alpha Antibody (Monoclonal, CN-A1) (MA1008).Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
Images And Assay Conditions
Boster Kit Box
Protein Target Info (Source: Uniprot.org)
|Protein Name||Calcineurin subunit B type 1|
|Tissue Specificity||Isoform 2 is testis specific. .|
|Alternative Names||Calcineurin subunit B type 1;Protein phosphatase 2B regulatory subunit 1;Protein phosphatase 3 regulatory subunit B alpha isoform 1;Ppp3r1;Cna2, Cnb;|
|Subcellular Localization||Cytoplasm, cytosol . Cell membrane ; Lipid-anchor . Cell membrane, sarcolemma. Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. .|
|Molecular Weight||19300 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.|
|Research Areas||Bovine, Human, Rat
*You can search these to find other products in these research areas.
|Background||Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha(PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase(calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast.|
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Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WBA: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugationA: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact [email protected]
Q: Can you provide monoclonal antibodies carrier free?A: For most of our monoclonal antibodies, we are unable to provide them carrier free. If you would like to check if a specific antibody can be provided carrier free, please send an email to [email protected]
Q: What are some alternative names that could be used to describe this product?A: One other very common name is ccn1 antibody