Anti-CaMKII Camk2d Antibody

Product Name

Anti-CaMKII Camk2d Antibody

View all CaM Kinase II delta Antibodies

SKU/Catalog Number

A02611

Size

50μg/vial

Form

Liquid

Description

Boster Bio Anti-CaMKII Camk2d Antibody catalog # A02611. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CaMKII Camk2d Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02611)

Host

Rabbit

Contents

Each vial contains 50% glycerol and 0.09% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide corresponding to the N-terminus of rat CaMKII δ.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A02611 is reactive to CAMK2D in Human, Mouse, Rat

Applications

A02611 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

56.369kDa

Background of CaM Kinase II delta

SOD3 (SUPEROXIDE DISMUTASE 3) also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al. (1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al. (2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is though to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, Colorimetric, 1:500, Human, Mouse, Rat

Validation Images & Assay Conditions

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CaMKII was detected in paraffin-embedded sections of human lung tissues using rabbit anti-CaMKII Antigen Affinity purified polyclonal antibody (Catalog # A02611) at 10 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).

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Western blot analysis of CaMKII expression in MW marker (lane 1), mouse brain extract (lane 2), rat brain extract (lane 3), HELA whole cell lysates (lane 4) and HS-67 whole cell lysates (lane 5). CaMKII at 50-60KD was detected using rabbit anti-CaMKII Antigen Affinity purified polyclonal antibody (Catalog # A02611) at 1: 500. The blot was developed using colorimetric method.

Gene/Protein Information For CAMK2D (Source: Uniprot.org, NCBI)

Alternative Names

calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II delta subunit; CaM Kinase II delta; CaM kinase II subunit delta; CAMK2D; CAMKD; CaMK-II delta subunit; CaMK-II subunit delta; CaM-kinase II delta chain; DKFZp686G23119; DKFZp686I2288; EC 2.7.11; EC 2.7.11.17; MGC44911 CAMK2D CAMKD calcium/calmodulin dependent protein kinase II delta calcium/calmodulin-dependent protein kinase type II subunit delta|CaM kinase II delta subunit|CaM-kinase II delta chain|CaMK-II delta subunit|calcium/calmodulin-dependent protein kinase (CaM kinase) II delta|calcium/calmodulin-dependent protein kinase type II delta chain

For more info on CAMK2D, check out the CAMK2D Infographic

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In this infographic, you will see the following information for CAMK2D: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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