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Product Info Summary
| SKU: | A07920 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CAPS2 CADPS2 Antibody
SKU/Catalog Number
A07920
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CAPS2 CADPS2 Antibody (Catalog # A07920). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CAPS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CAPS2 CADPS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07920)
Host
Rabbit
Contents
CAPS2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CAPS2 antibody was raised against a 19 amino acid synthetic peptide near the center of the human CAPS2. The immunogen is located within amino acids 510 - 560 of CAPS2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of CAPS2 are known to exist. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.
Reactive Species
A07920 is reactive to CADPS2 in Human, Mouse, Rat
Applications
A07920 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
147.735kDa
Background of CADPS2
CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CAPS2 antibody can be used for detection of CAPS2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CAPS2 in human brain tissue lysate with CAPS2 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of CAPS2 in human brain with CAPS2 antibody at 5 μg/mL.
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Immunofluorescence of CAPS2 in Human Brain tissue with CAPS2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CADPS2 (Source: Uniprot.org, NCBI)
Gene Name
CADPS2
Full Name
Calcium-dependent secretion activator 2
Weight
147.735kDa
Alternative Names
Nothing Found CADPS2 CAPS2 calcium dependent secretion activator 2 calcium-dependent secretion activator 2|CAPS-2|Ca++-dependent secretion activator 2|Ca2+ dependent secretion activator 2|Ca2+-dependent activator protein for secretion 2|calcium-dependent activator protein for secretion 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CADPS2, check out the CADPS2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CADPS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CAPS2 CADPS2 Antibody (A07920)
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No publications found for A07920
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Customer Reviews
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