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- Table of Contents
CARD10 antibody (A07686-2) performs well in ELISA, IHC-P and shows reactivity with Human.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunohistochemistry of CARMA3 in human kidney tissue with CARMA3 antibody at 5 μg/ml
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Anti-CARMA3 CARD10 Antibody
CARD10 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human | Rabbit | ELISA, IHC-P |
Recommend Dilution
Application
Dilution
Species
CARMA3 antibody can be used for detection of CARMA3 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-CARMA3 CARD10 Antibody
View all CARD10 Antibodies
View all CARD10 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
CARMA3 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
CARMA3 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CARMA3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CARMA3. The immunogen is located within the first 50 amino acids of CARMA3.
Cross-Reactivity
CARMA3 antibody is human specific. At least three isoforms of CARMA3 are known to exist; this antibody will only detect isoform 1. CARMA3 antibody is predicted not to cross-react with other CARMA proteins.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
115.9 kDa
Background of CARD10
CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA3 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-κB activation. When expressed in cells, this protein binds to BCL10 and activates NF-κB Recent experiments have shown that CARMA3 is required for EGF-induced NF-κB activation and contributes to tumor growth in vivo, suggesting that CARMA3 may serve as a new therapeutic target for the treatment of EGFR-driven tumors.
Cite This Product
Anti-CARMA3 CARD10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07686-2)
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Product Promise
We promise Anti-CARMA3 CARD10 Antibody performs excellently in relevant applications for ELISA, IHC-P. If it doesn't perform as promised, we will refund the product. Learn more
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A07686-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 16, 2026