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Product Info Summary
| SKU: | A32138 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-CASC5 KNL1 Antibody
SKU/Catalog Number
A32138
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CASC5 KNL1 Antibody catalog # A32138. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CASC5 KNL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A32138)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Pragmin around the phosphorylation site of Y413.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A32138 is reactive to KNL1 in Human, Rat
Applications
A32138 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
265.391kDa
Background of KNL1
Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-CASC5 KNL1 Antibody A32138
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For KNL1 (Source: Uniprot.org, NCBI)
Gene Name
KNL1
Full Name
Kinetochore scaffold 1
Weight
265.391kDa
Alternative Names
Kinetochore scaffold 1 KNL1 AF15Q14, CASC5, CT29, D40, MCPH4, PPP1R55, Spc7, hKNL-1, hSpc105 kinetochore scaffold 1 kinetochore scaffold 1|ALL1-fused gene from chromosome 15q14 protein|blinkin, bub-linking kinetochore protein|cancer susceptibility candidate 5|cancer susceptibility candidate gene 5 protein|cancer/testis antigen 29|kinetochore null 1 homolog|kinetochore-null protein 1|microcephaly, primary autosomal recessive 4|protein phosphatase 1, regulatory subunit 55
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KNL1, check out the KNL1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KNL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CASC5 KNL1 Antibody (A32138)
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No publications found for A32138
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Customer Reviews
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