Product Info Summary
SKU: | A02398T251 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Casein Kinase II Alpha (T251) CSNK2A1 Antibody
View all Casein Kinase 2 alpha Antibodies
SKU/Catalog Number
A02398T251
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Casein Kinase II Alpha (T251) CSNK2A1 Antibody catalog # A02398T251. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Casein Kinase II Alpha (T251) CSNK2A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02398T251)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Casein Kinase IIalpha around the non-phosphorylation site of Y255.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02398T251 is reactive to CSNK2A1 in Human, Mouse, Rat
Applications
A02398T251 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
45.144kDa
Background of Casein Kinase 2 alpha
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001)
Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)
Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)
Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:4000
IHC: 1:50-1:200
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of CSNK2A1 using Anti-Casein Kinase II Alpha (T251) CSNK2A1 Antibody (A02398T251).
Immunohistochemistry (IHC) analyzes of Casein Kinase IIα (T251) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibodyProtein Target Info & Infographic
Gene/Protein Information For CSNK2A1 (Source: Uniprot.org, NCBI)
Gene Name
CSNK2A1
Full Name
Casein kinase II subunit alpha
Weight
45.144kDa
Superfamily
protein kinase superfamily
Alternative Names
Casein Kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 subunit; CK II alpha; CK2 catalytic subunit alpha; CK2A1; CK2A1casein kinase II subunit alpha; CKII; CSNK2A1; EC 2.7.11; EC 2.7.11.1; protein kinase CK2 CSNK2A1 CK2A1, CKII, Cka1, Cka2, OCNDS casein kinase 2 alpha 1 casein kinase II subunit alpha|CK2 catalytic subunit alpha|casein kinase 2, alpha 1 polypeptide|casein kinase II alpha 1 polypeptide pseudogene|casein kinase II alpha 1 subunit|protein kinase CK2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CSNK2A1, check out the CSNK2A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CSNK2A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Casein Kinase II Alpha (T251) CSNK2A1 Antibody (A02398T251)
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No publications found for A02398T251
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