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Product Info Summary
| SKU: | A02468 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CASK Antibody
SKU/Catalog Number
A02468
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CASK Antibody (Catalog # A02468). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CASK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CASK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02468)
Host
Rabbit
Contents
CASK Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
CASK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CASK. The immunogen is located within amino acids 760 - 810 of CASK.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least six alternatively spliced transcript variants have been observed.
Reactive Species
A02468 is reactive to CASK in Human, Mouse, Rat
Applications
A02468 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
105.123kDa
Background of CASK
CASK (Calcium/calmodulin-dependent serine protein kinase), a conserved multi-domain scaffolding protein, belongs to a MAGUK (membrane-associated guanylate kinase homologs) subfamily and is involved in cell junction organization, tumor suppression and signaling. It is characterized by a novel domain structure that consists of a calcium/calmodulin-dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is ubiquitously expressed and significantly greater in brain where it is thought to be involved in signaling at neuronal synapses. CASK interacts with CASKINs and defects in CASK are the cause of mental retardation X-linked CASK-related.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CASK antibody can be used for detection of CASK by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CASK in mouse brain tissue lysate with CASK antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of CASK in human brain tissue with CASK antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CASK (Source: Uniprot.org, NCBI)
Gene Name
CASK
Full Name
Peripheral plasma membrane protein CASK
Weight
105.123kDa
Superfamily
MAGUK family
Alternative Names
calcium/calmodulin-dependent serine protein kinase (MAGUK family); calcium/calmodulin-dependent serine protein kinase membrane-associatedguanylate kinase; Calcium/calmodulin-dependent serine protein kinase; CAMGUK; CMG; EC 2.7.11; EC 2.7.11.1; FGS4CAGH39; FLJ22219; hCASK; LIN2FLJ31914; MICPCH; peripheral plasma membrane protein CASK; Protein lin-2 homolog; TNRC8; trinucleotide repeat containing 8 CASK CAGH39, CAMGUK, CMG, FGS4, LIN2, MICPCH, MRXSNA, TNRC8, hCASK calcium/calmodulin dependent serine protein kinase peripheral plasma membrane protein CASK|calcium/calmodulin-dependent serin protein kinase|calcium/calmodulin-dependent serine protein kinase (MAGUK family)|calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase|protein lin-2 homolog|trinucleotide repeat containing 8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CASK, check out the CASK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CASK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CASK Antibody (A02468)
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No publications found for A02468
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Customer Reviews
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