Anti-Caspase-3 (P10)/CASP3 Antibody

Boster Bio Anti-Caspase-3 (P10)/CASP3 Antibody catalog # PA1302-1. Tested in IHC-P, ICC, WB applications. This antibody reacts with Human. Cited in 103 publication(s). Independently reviewed in 1 review(s).

Product Info Summary

SKU: PA1302-1
Size: 100μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC-P, ICC, WB

Product Name

Anti-Caspase-3 (P10)/CASP3 Antibody

See all Caspase-3 products

SKU/Catalog Number







Boster Bio Anti-Caspase-3 (P10)/CASP3 Antibody catalog # PA1302-1. Tested in IHC-P, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Caspase-3 (P10)/CASP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1302-1)




Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.




A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-3 (P10) (220-236aa CAMLKQYADKLEFMHIL).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1302-1 is reactive to CASP3 in Human


PA1302-1 is guaranteed for IHC-P, ICC, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Immunocytochemistry , 0.5-1μg/ml, Human, -
Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For CASP3 (Source: Uniprot.Org, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name





peptidase C14A family

Alternative Names

Apopain; apoptosis-related cysteine protease; CASP3; CASP-3; caspase 3, apoptosis-related cysteine peptidase; Caspase3; Caspase-3; CPP32; CPP-32; CPP32B; CPP32SREBP cleavage activity 1; Cysteine protease CPP32; EC 3.4.22; EC; LICE-1; PARP cleavage protease; procaspase3; Protein Yama; SCA-1; YAMA CASP3 CPP32, CPP32B, SCA-1 caspase 3 caspase-3|CASP-3|CPP-32|PARP cleavage protease|SREBP cleavage activity 1|apopain|caspase 3, apoptosis-related cysteine peptidase|caspase 3, apoptosis-related cysteine protease|cysteine protease CPP32|procaspase3|protein Yama

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on CASP3, check out the CASP3 Infographic

CASP3 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for CASP3: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PA1302-1 has been cited in 103 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Ahmed S. Ahmed,JAK-1/STAT-3 pathway mediated role in aging cerebellar cortex degenerative changes of albino wistar rats, Translational Research in Anatomy, 2020,100089,ISSN 2214-854X, 1016/j.tria.2020.100089.
Species: Rat
PA1302-1 usage in article: APP:IHC, SAMPLE:CEREBELLAR CORTEX, DILUTION:1:200

Gang Li,Jing Zhou,Mengyu Sun,Juren Cen,Jing Xu,Role of luteolin extracted from Clerodendrum cyrtophyllum Turcz leaves in protecting HepG2 cells from TBHP-induced oxidative stress and its cytotoxicity, genotoxicity,Journal of Functional Foods, Volume 74, 2
Species: Human
PA1302-1 usage in article: APP:WB, SAMPLE:HEPG-2 CELL, DILUTION:1:2000

Yu Y,Wang Y,Fei X,Song Z,Xie F,Yang F,Liu X,Xu Z,Wang G.All-Trans Retinoic Acid Prevented Vein Grafts Stenosis by Inhibiting Rb-E2F Mediated Cell Cycle Progression and KLF5-RARα Interaction in Human Vein Smooth Muscle Cells.Cardiovasc Drugs Ther.2020 Oct
Species: Human,New Zealand White Rabbit
PA1302-1 usage in article: APP:WB, SAMPLE:HUVMSCS, DILUTION:1:1000

Liu L,Liu F,Sun Z,Peng Z,You T,Yu Z. LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p. Exp Ther Med.2020 Oct; 20(4):3290-3300. doi:10.3892/etm.2020.9079. Epub 2020 Jul 29.PMID:32855700;PMCID:PMC7444425.
Species: Human

Sun K,Luo J,Jing X,Xiang W,Guo J,Yao X,Liang S,Guo F,Xu T.Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.Phytomedicine.2020 Oct 14;80:153387.doi:10.1016/j.phymed.2020. 153387.Epub ahead of print.PMID:33130473.
Species: Mouse
PA1302-1 usage in article: APP:WB, SAMPLE:CHONDROCYTES, DILUTION:1:1000

Yue W,Cunlin G,Lu H,Yuanqing Z,Yanjun T,Qiong W. Neuroprotective effect of intermittent hypobaric hypoxia preconditioning on cerebral ischemia/reperfusion in rats. Int J Clin Exp Pathol.2020 Nov 1;13(11):2860-2869.PMID:33284899;PMCID:PMC7716138.
Species: Rat
PA1302-1 usage in article: APP:WB, SAMPLE:NEURONS, DILUTION:1:1500

Maternal separation exacerbates Alzheimer's disease-like behavioral and pathological changes in adult APPswe/PS1dE9 mice

MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/%u03B2-catenin signaling

Diabetes Inhibits Cerebral Ischemia-Induced Astrocyte Activation - an Observation in the Cingulate Cortex

Hepatitis E Virus Induces Hepatocyte Apoptosis via Mitochondrial Pathway in Mongolian Gerbils

Effects of Bushen Tianjing Recipe in a rat model of tripterygium glycoside-induced premature ovarian failure

Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir

A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis

Optimal concentration and time window for proliferation and differentiation of neural stem cells from embryonic cerebral cortex: 5% oxygen preconditioning for 72 hours

Ulinastatin suppresses endoplasmic reticulum stress and apoptosis in the hippocampus of rats with acute paraquat poisoning

Liraglutide prevents fast weight gain and ?-cell dysfunction in male catch-up growth rats

Nutlin-3 downregulates p53 phosphorylation on serine392and induces apoptosis in hepatocellular carcinoma cells

In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures

Enhanced anti-apoptosis and gut epithelium protection function of acidic fibroblast growth factor after cancelling of its mitogenic activity

Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats

Chinese herbal medicine Yougui Pill reduces exogenous glucocorticoid-induced apoptosis in anterior pituitary cells

Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma

Nerve growth factor reduces apoptotic cell death in rat facial motor neurons after facial nerve injury

Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction

In vivo?and?in vitro?evaluation of the cytotoxic effects of Photosan-loaded hollow silica nanoparticles on liver cancer

Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization

Qi QM, Xue YC, Lv J, Sun D, Du JX, Cai SQ, Li YH, Gu TC, Wang MB. Oncol Lett. 2018 May;15(5):6400-6408. doi: 10.3892/ol.2018.8177. Epub 2018 Mar 5. Ginkgolic acids induce HepG2 cell death via a combination of apoptosis, autophagy and the mitochond...

An J, Liu T, She R, Wu Q, Tian J, Shi R, Hao W, Ren X, Yang Y, Lu Y, Yang Y, Wu Y. Oncotarget. 2017 Dec 17;9(4):4475-4484. doi: 10.18632/oncotarget.23381. eCollection 2018 Jan 12. Replication of hepatitis E virus in the ovary and promotion of oocy...

Sun X, Cui M, Wang D, Guo B, Zhang L. Oncol Lett. 2018 Apr;15(4):5744-5750. doi: 10.3892/ol.2018.8071. Epub 2018 Feb 16. Tumor necrosis factor-related apoptosis inducing ligand overexpression and Taxol treatment suppresses the growth of cervical c...

Feng D, Wu J, Tian Y, Zhou H, Zhou Y, Hu W, Zhao W, Wei H, Ling B, Ma C. Plos One. 2013 Nov 19;8(11):E80657. Doi: 10.1371/Journal.Pone.0080657. Ecollection 2013. Targeting Of Histone Deacetylases To Reactivate Tumour Suppressor Genes And Its Thera...

Qian C,, Gong L, Yang Z, Chen W, Chen Y, Xu Z, Wu B, Tang C, Gao F, Zeng W,. Bmc Cardiovasc Disord. 2015 Jun 26;15:59. Doi: 10.1186/S12872-015-0046-9. Diastolic Dysfunction In Spontaneous Type 2 Diabetes Rhesus Monkeys: A Study Using Echocardiogra...

Feng H, Yin Sh, Tang Az, Tan Sh. Neurochem Res. 2011 Jun;36(6):1108-15. Doi: 10.1007/S11064-011-0455-9. Epub 2011 Mar 31. Salicylate Initiates Apoptosis In The Spiral Ganglion Neuron Of Guinea Pig Cochlea By Activating Caspase-3.

Liang J, Chen H, Pan W, Xu C. Mol Med Rep. 2012 Jun;5(6):1419-22. Doi: 10.3892/Mmr.2012.854. Epub 2012 Apr 2. Puerarin Inhibits Caspase-3 Expression In Osteoblasts Of Diabetic Rats.

Jia Y, Lin J, Mi Y, Zhang C. Reprod Toxicol. 2011 May;31(4):477-85. Doi: 10.1016/J.Reprotox.2010.12.057. Epub 2011 Jan 22. Quercetin Attenuates Cadmium-Induced Oxidative Damage And Apoptosis In Granulosa Cells From Chicken Ovarian Follicles.

Zhang T, Su J, Wang K, Zhu T, Li X. Neurosci Lett. 2014 Sep 5;579:12-7. Doi: 10.1016/J.Neulet.2014.07.005. Epub 2014 Jul 12. Ursolic Acid Reduces Oxidative Stress To Alleviate Early Brain Injury Following Experimental Subarachnoid Hemorrhage.

Li Ys, Chen Bf, Li Xj, Zhang Wk, Tang Hb. Plos One. 2014 Sep 24;9(9):E107361. Doi: 10.1371/Journal.Pone.0107361. Ecollection 2014. Cytotoxicity Of Polyaniline Nanomaterial On Rat Celiac Macrophages In Vitro.

Zhang L, Yu S, Duan Z, Wang Q, Tian G, Tian Y, Zhao W, Wang H, Zhang C, Guo S, Liu Q, He G, Bian T, Chang J, Jin X, Cui D. Int J Mol Med. 2014 Jan;33(1):117-27. Doi: 10.3892/Ijmm.2013.1542. Epub 2013 Oct 30. Treatment Of Liver Cancer In Mice By Th...

Hu K, Xie Yy, Zhang C, Ouyang Ds, Long Hy, Sun Dn, Long Ll, Feng L, Li Y, Xiao B. Bmc Neurosci. 2012 Sep 22;13:115. Doi: 10.1186/1471-2202-13-115. Microrna Expression Profile Of The Hippocampus In A Rat Model Of Temporal Lobe Epilepsy And Mir-34A-...

Liu Nb, Peng T, Pan C, Yao Yy, Shen B, Leng J. World J Gastroenterol. 2005 Oct 28;11(40):6281-7. Overexpression Of Cyclooxygenase-2 In Human Hepg2, Bel-7402 And Smmc-7721 Hepatoma Cell Lines And Mechanism Of Cyclooxygenase-2 Selective Inhibitor Ce...

Li Z, Shao S, Xie S, Jiao F, Ma Y, Shi S. Ir J Med Sci. 2010 Jun;179(2):217-23. Doi: 10.1007/S11845-009-0418-1. Epub 2009 Dec 20. Silencing Of Ct120 By Antisense Oligonucleotides Could Inhibit The Lung Cancer Cells Growth.

Feng H, Yin Sh, Tang Az, Cai Hw, Chen P, Tan Sh, Xie Lh. Neurosci Lett. 2010 Jul 19;479(1):34-9. Doi: 10.1016/J.Neulet.2010.05.023. Epub 2010 May 15. Caspase-3 Activation In The Guinea Pig Cochlea Exposed To Salicylate.

Zhang S, Li H, Yang Sj. Acta Pharmacol Sin. 2010 Jun;31(6):671-8. Doi: 10.1038/Aps.2010.45. Epub 2010 May 10. Tribulosin Protects Rat Hearts From Ischemia/Reperfusion Injury.

Sun Mm, Li Jf, Guo Ll, Xiao Ht, Dong L, Wang F, Huang Fb, Cao D, Qin T, Yin Xh, Li Jm, Wang Sl. Oncogene. 2014 Apr 17;33(16):2075-86. Doi: 10.1038/Onc.2013.165. Epub 2013 May 13. Tgf-??1 Suppression Of Microrna-450B-5P Expression: A Novel Mechanis...

Oztanir Mn, Ciftci O, Cetin A, Aladag Ma. Neurol Sci. 2014 Sep;35(9):1393-9. Doi: 10.1007/S10072-014-1725-5. Epub 2014 Mar 28. Hesperidin Attenuates Oxidative And Neuronal Damage Caused By Global Cerebral Ischemia/Reperfusion In A C57Bl/J6 Mouse M...

Ciftci O, Oztanir Mn, Cetin A. Neurochem Res. 2014 Sep;39(9):1717-23. Doi: 10.1007/S11064-014-1365-4. Epub 2014 Jun 28. Neuroprotective Effects Of ??-Myrcene Following Global Cerebral Ischemia/Reperfusion-Mediated Oxidative And Neuronal Damage In ...

Chen Y, Li D, Xu Y, Zhang Y, Tao L, Li S, Jiang Y, Shen X. Evid Based Complement Alternat Med. 2014;2014:956824. Doi: 10.1155/2014/956824. Epub 2014 Dec 23. Essential Oils From Fructus A. Zerumbet Protect Human Aortic Endothelial Cells From Apopto...

Zhou X, Zhang Y, Li Y, Hao X, Liu X, Wang Y. Cancers (Basel). 2012 Dec 4;4(4):1318-32. Doi: 10.3390/Cancers4041318. Azithromycin Synergistically Enhances Anti-Proliferative Activity Of Vincristine In Cervical And Gastric Cancer Cells.

Li Q, Li Z, Xu Xy, Guo Yl, Du F. Int J Mol Sci. 2010 Nov 16;11(11):4580-90. Doi: 10.3390/Ijms11114580. Neuroprotective Properties Of Picroside Ii In A Rat Model Of Focal Cerebral Ischemia.

Chang C, Liu Sp, Fang Ch, He Rs, Wang Z, Zhu Yq, Jiang Sw. Oncol Lett. 2013 Sep;6(3):699-704. Epub 2013 Jul 8. Effects Of Matrine On The Proliferation Of Ht29 Human Colon Cancer Cells And Its Antitumor Mechanism.

Shu Hf, Yu Sx, Zhang Cq, Liu Sy, Wu Kf, Zang Zl, Yang H, Zhou Sw, Yin Q. Brain Dev. 2013 Mar;35(3):252-60. Doi: 10.1016/J.Braindev.2012.04.007. Epub 2012 May 28. Expression Of Trpv1 In Cortical Lesions From Patients With Tuberous Sclerosis Complex...

Wang Xf, Qu Xq, Zhang Tt, Zhang Jf. Exp Ther Med. 2015 Apr;9(4):1283-1291. Epub 2015 Feb 6. Testosterone Suppresses Ventricular Remodeling And Improves Left Ventricular Function In Rats Following Myocardial Infarction.

Li M, Peng J, Song Y, Liang H, Mei Y, Fang Y. J Huazhong Univ Sci Technolog Med Sci. 2012 Oct;32(5):746-9. Doi: 10.1007/S11596-012-1028-0. Epub 2012 Oct 18. Electro-Acupuncture Combined With Transcranial Magnetic Stimulation Improves Learning And ...

Wu Z, Wang L, Hou S. Neural Regen Res. 2012 Jul 5;7(19):1493-7. Doi: 10.3969/J.Issn.1673-5374.2012.19.008. Alpha B-Crystallin Improved Survival Of Retinal Ganglion Cells In A Rat Model Of Acute Ocular Hypertension.

Chen A, Dang T, Wang S, Tang N, Liu Y, Wu W. Sci China Life Sci. 2014 Jul;57(7):698-709. Doi: 10.1007/S11427-014-4680-8. Epub 2014 Jun 16. The In Vitro And In Vivo Anti-Tumor Effects Of Mtx-Fe3O 4-Plla-Peg-Plla Microspheres Prepared By Suspension-...

Yuan X, Sun Q, Ou Y, Wang S, Zhang W, Deng H, Wu X, Zhang L. Neural Regen Res. 2014 Apr 15;9(8):837-44. Doi: 10.4103/1673-5374.131600. Apoptosis Is An Obstacle To The Differentiation Of Adipose-Derived Stromal Cells Into Astrocytes.

Chen S, Peng H, Rowat A, Gao F, Zhang Z, Wang P, Zhang W, Wang X, Qu L. Brain Res. 2015 Aug 27;1618:205-11. Doi: 10.1016/J.Brainres.2015.05.027. Epub 2015 May 30. The Effect Of Concentration And Duration Of Normobaric Oxygen In Reducing Caspase-3 ...

Dai C, Li J, Tang S, Li J, Xiao X. Antimicrob Agents Chemother. 2014 Jul;58(7):4075-85. Doi: 10.1128/Aac.00070-14. Epub 2014 May 5. Colistin-Induced Nephrotoxicity In Mice Involves The Mitochondrial, Death Receptor, And Endoplasmic Reticulum Pathw...

Ji J, Yan X, Li Z, Lai Z, Liu J. Biomed Pharmacother. 2015 Feb;69:311-6. Doi: 10.1016/J.Biopha.2014.12.020. Epub 2014 Dec 19. Therapeutic Effects Of Intrathecal Versus Intravenous Monosialoganglioside Against Bupivacaine-Induced Spinal Neurotoxici...

Lin Hd, He Cq, Luo Ql, Zhang Jl, Zeng Dx. Rheumatol Int. 2012 Mar;32(3):759-66. Doi: 10.1007/S00296-010-1629-5. Epub 2010 Dec 28. The Effect Of Low-Level Laser To Apoptosis Of Chondrocyte And Caspases Expression, Including Caspase-8 And Caspase-3 ...

Guo H, Luo Q, Zhang J, Lin H, Xia L, He C. Joint Bone Spine. 2011 Dec;78(6):604-10. Doi: 10.1016/J.Jbspin.2011.01.009. Epub 2011 Mar 11. Comparing Different Physical Factors On Serum Tnf-?? Levels, Chondrocyte Apoptosis, Caspase-3 And Caspase-8 Ex...

Zeng D, Luo Q, Lin H, Zhang J, He C. Rheumatol Int. 2012 Dec;32(12):3771-7. Doi: 10.1007/S00296-011-2196-0. Epub 2011 Dec 14. The Effect Of Therapeutic Ultrasound To Apoptosis Of Chondrocyte And Caspase-3 And Caspase-8 Expression In Rabbit Surgery...

Shan S, Li Z, Newton Ip, Zhao C, Li Z, Guo M. Toxicol Lett. 2014 Jun 5;227(2):129-38. Doi: 10.1016/J.Toxlet.2014.03.008. Epub 2014 Mar 28. A Novel Protein Extracted From Foxtail Millet Bran Displays Anti-Carcinogenic Effects In Human Colon Cancer ...

Zhao X, Chen Q, Li Y, Tang H, Liu W, Yang X. Eur J Pharm Biopharm. 2015 Jun;93:27-36. Doi: 10.1016/J.Ejpb.2015.03.003. Epub 2015 Mar 11. Doxorubicin And Curcumin Co-Delivery By Lipid Nanoparticles For Enhanced Treatment Of Diethylnitrosamine-Induc...

Lin S, Lin K, Li W, Zhou X, Huang T. Endocrine. 2010 Jun;37(3):460-6. Doi: 10.1007/S12020-010-9337-1. Epub 2010 Apr 21. Maternal Diabetes Increases Apoptosis In Mice Oocytes, Not 2-Cell Embryos.

Du F, Ding Y, Zou J, Li Z, Tian J, She R, Wang D, Wang H, Lv D, Chang L. Plos One. 2015 May 22;10(5):E0127047. Doi: 10.1371/Journal.Pone.0127047. Ecollection 2015. Morphology And Molecular Mechanisms Of Hepatic Injury In Rats Under Simulated Weigh...

Li Tt, Zhang Jf, Fei Sj, Zhu Sp, Zhu Jz, Qiao X, Liu Zb. Acta Pharmacol Sin. 2014 Feb;35(2):185-94. Doi: 10.1038/Aps.2013.140. Epub 2013 Dec 23. Glutamate Microinjection Into The Hypothalamic Paraventricular Nucleus Attenuates Ulcerative Colitis I...

Li Wz, Li Wp, Huang Dk, Kan Hw, Wang X, Wu Wy, Yin Yy, Yao Yy. Behav Brain Res. 2012 Feb 1;227(1):142-9. Doi: 10.1016/J.Bbr.2011.10.038. Epub 2011 Oct 29. Dexamethasone And A????????-?????? Accelerate Learning And Memory Impairments Due To Elevate...

Lu Y, Yuan X, Ou Y, Cai Y, Wang S, Sun Q, Zhang W. Neural Regen Res. 2012 Jun 5;7(16):1205-12. Doi: 10.3969/J.Issn.1673-5374.2012.16.001. Autophagy And Apoptosis During Adult Adipose-Derived Stromal Cells Differentiation Into Neuron-Like Cells In ...

Chu Sh, Ma Yb, Feng Df, Zhang H, Qiu Jh, Zhu Za. Oncol Lett. 2011 Nov;2(6):1139-1142. Epub 2011 Aug 4. Elevated Expression Of Solute Carrier Family 22 Member 18 Increases The Sensitivity Of U251 Glioma Cells To Bcnu.

Zhao B, Li X. Oncol Rep. 2014 Jun;31(6):2769-75. Doi: 10.3892/Or.2014.3126. Epub 2014 Apr 3. Altholactone Induces Reactive Oxygen Species-Mediated Apoptosis In Bladder Cancer T24 Cells Through Mitochondrial Dysfunction, Mapk-P38 Activation And Akt...

Zhan W, Hu X, Yi J, An Q, Huang X. Mol Med Rep. 2015 Jun;11(6):4142-8. Doi: 10.3892/Mmr.2015.3326. Epub 2015 Feb 10. Inhibitory Activity Of Apogossypol In Human Prostate Cancer In Vitro And In Vivo.

Kan S, Zhou H, Jin C, Yang H. Int J Clin Exp Med. 2015 Mar 15;8(3):3258-70. Ecollection 2015. Effects Of Pdtc On Nf-??b Expression And Apoptosis In Rats With Severe Acute Pancreatitis-Associated Lung Injury.

Wang Jm, Xiao Bl, Zheng Jw, Chen Hb, Zou Sq. World J Gastroenterol. 2007 Jun 21;13(23):3171-5. Effect Of Targeted Magnetic Nanoparticles Containing 5-Fu On Expression Of Bcl-2, Bax And Caspase 3 In Nude Mice With Transplanted Human Liver Cancer.

Meng Qt, Xia Zy, Luo T, Cao C, Zhao B, Wu Y, Wu X, Chen X. Saudi Med J. 2012 Feb;33(2):139-45. Ligustrazine Attenuates Acute Lung Injury Induced By Blunt Chest Trauma.

Zhou Y, Li W, Xu Q, Huang Y. J Exp Clin Cancer Res. 2010 Oct 4;29:131. Doi: 10.1186/1756-9966-29-131. Elevated Expression Of Dickkopf-1 Increases The Sensitivity Of Human Glioma Cell Line Shg44 To Bcnu.

Rasul A, Yu B, Khan M, Zhang K, Iqbal F, Ma T, Yang H. Int J Oncol. 2012 Apr;40(4):1153-61. Doi: 10.3892/Ijo.2011.1277. Epub 2011 Nov 30. Magnolol, A Natural Compound, Induces Apoptosis Of Sgc-7901 Human Gastric Adenocarcinoma Cells Vi...

Peng X, Chen K, Chen J, Fang J, Cui H, Zuo Z, Deng J, Chen Z, Geng Y, Lai W. Environ Toxicol. 2015 Mar 4. Doi: 10.1002/Tox.22120. [Epub Ahead Of Print] Aflatoxin B1 Affects Apoptosis And Expression Of Bax, Bcl-2, And Caspase-3 In Thymus And Bursa ...

Chen J, Li X, Qiu J, You H, Zhang Q, Dong G, Zuo Y. Cell Biochem Biophys. 2013;67(3):1015-9. Doi: 10.1007/S12013-013-9597-5. Kinetics Of Apoptosis And Expression Of Apoptosis-Related Proteins In Rat Ca3 Hippocampus Cells After Experimental Diffuse...

Liu Y, Zhou Y, Wang Y, Geng D, Liu J. Obes Surg. 2011 Sep;21(9):1424-31. Doi: 10.1007/S11695-011-0388-Z. Roux-En-Y Gastric Bypass-Induced Improvement Of Glucose Tolerance And Insulin Resistance In Type 2 Diabetic Rats Are Mediated By Glucagon-Like...

Yang Y, Li Zh, Liu H, Shi Wd, Zhang J. Chin J Integr Med. 2015 Jun;21(6):423-30. Doi: 10.1007/S11655-014-1752-3. Epub 2014 May 10. Inhibitory Effect Of Tetramethylpyrazine Preconditioning On Overload Training-Induced Myocardial Apoptosis In Rats.

Song Gh, Wang Rl, Chen Zy, Zhang B, Wang Hl, Liu Ml, Gao Jp, Yan Xy. J Physiol Biochem. 2014 Sep;70(3):761-8. Doi: 10.1007/S13105-014-0344-1. Epub 2014 Jul 30. Toxic Effects Of Sodium Fluoride On Cell Proliferation And Apoptosis Of Leydig Cells Fr...

Chen K, Shu G, Peng X, Fang J, Cui H, Chen J, Wang F, Chen Z, Zuo Z, Deng J, Geng Y, Lai W. Food Chem Toxicol. 2013 Sep;59:446-54. Doi: 10.1016/J.Fct.2013.06.032. Epub 2013 Jun 28. Protective Role Of Sodium Selenite On Histopathological Lesions, D...

Mao Z, Song Z, Li G, Lv W, Zhao X, Li B, Feng X, Chen Y. Neural Regen Res. 2013 Jan 15;8(2):133-42. Doi: 10.3969/J.Issn.1673-5374.2013.02.005. 8-Hydroxy-2-(Di-N-Propylamino)Tetralin Intervenes With Neural Cell Apoptosis Following Diffuse Axonal In...

Yan Y, Liang B, Zhang J, Liu Y, Bu X. Mol Med Rep. 2015 Jan;11(1):317-26. Doi: 10.3892/Mmr.2014.2657. Epub 2014 Oct 15. Apoptotic Induction Of Lung Adenocarcinoma A549 Cells Infected By Recombinant Rvg Newcastle Disease Virus (Rl-Rvg) In Vitro.

Li X, Wang L, Wang Z. Phys Med. 2015 Jun;31(4):352-9. Doi: 10.1016/J.Ejmp.2015.02.004. Epub 2015 Feb 19. Radioprotective Activity Of Neutral Polysaccharides Isolated From The Fruiting Bodies Of Hohenbuehelia Serotina.

Wei T, Tian W, Yan H, Shao G, Xie G. Cell Mol Neurobiol. 2014 Nov;34(8):1165-73. Doi: 10.1007/S10571-014-0091-4. Epub 2014 Aug 22. Protective Effects Of Phillyrin On H2O 2-Induced Oxidative Stress And Apoptosis In Pc12 Cells.

Ding H, Wang H, Zhao Y, Sun D, Zhai X. Cell Mol Neurobiol. 2015 Jul;35(5):623-32. Doi: 10.1007/S10571-015-0156-Z. Epub 2015 Jan 18. Protective Effects Of Baicalin On A??????????????-Induced Learning And Memory Deficit, Oxidative Stress, And Apopto...

Xu S, Liu J, Zhang Y, Wang C, Wang J, Yang Y, Huo J, Sun W. Neural Regen Res. 2012 Jun 15;7(17):1318-24. Doi: 10.3969/J.Issn.1673-5374.2012.17.006. Apoptosis-Related Protein Expression In Rabbits With Blast Brain Injury Following Early Hyperbaric ...

Khan M, Li T, Ahmad Khan Mk, Rasul A, Nawaz F, Sun M, Zheng Y, Ma T. Biomed Res Int. 2013;2013:719858. Doi: 10.1155/2013/719858. Epub 2012 Dec 27. Alantolactone Induces Apoptosis In Hepg2 Cells Through Gsh Depletion, Inhibition Of Stat3 Activation...

Tian W, Wei T, Li B, Wang Z, Zhang N, Xie G. Plos One. 2014 May 6;9(5):E96775. Doi: 10.1371/Journal.Pone.0096775. Ecollection 2014. Pathway Of Programmed Cell Death And Oxidative Stress Induced By ??-Hydroxybutyrate In Dairy Cow Abomasum Smooth Mu...

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1 Reviews For Anti-Caspase-3 (P10)/CASP3 Antibody


"Excellent Caspase-3 Antibody from Boster Bio"



"Excellent Caspase-3 Antibody from Boster Bio"

--Mostafa Gabr, Duke University Hospital, Neurosurgery, Postdoctoral Researcher

Application Immunohistochemistry
Sample Rat spinal cord
Detection Fluorescent microscope

"I purchased this product to stain rat spinal cords exposed to injury. The injured spinal cords showed apoptotic cells obviously. Injured spinal cord sample showed high apoptosis compared to control (uninjured) spinal cord. Excellent, reliable product and easy to use."

Verified customer


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17 Customer Q&As for Anti-Caspase-3 (P10)/CASP3 Antibody


I see that the anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 works with ICC, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2020-04-22


You can find protocols for ICC on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2020-04-22


We have observed staining in human cervix carcinoma erythroleukemia. Are there any suggestions? Is anti-Caspase-3 (P10)/CASP3 antibody supposed to stain cervix carcinoma erythroleukemia positively?

Verified Customer

Verified customer

Asked: 2020-04-14


From what I have seen in literature cervix carcinoma erythroleukemia does express CASP3. From what I have seen in, CASP3 is expressed in jejunal mucosa, t-cell, tongue, lymph, cervix carcinoma erythroleukemia, among other tissues. Regarding which tissues have CASP3 expression, here are a few articles citing expression in various tissues:
Cervix carcinoma, and Erythroleukemia, Pubmed ID: 23186163
Lymph, Pubmed ID: 15489334
T-cell, Pubmed ID: 7983002, 7774019
Tongue, Pubmed ID: 14702039

Boster Scientific Support

Answered: 2020-04-14


We need to test anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 on human jejunal mucosa for research purposes, then I may be interested in using anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2020-03-06


The products we sell, including anti-Caspase-3 (P10)/CASP3 antibody PA1302-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2020-03-06


Is a blocking peptide available for product anti-Caspase-3 (P10)/CASP3 antibody (PA1302-1)?

Verified Customer

Verified customer

Asked: 2019-11-25


We do provide the blocking peptide for product anti-Caspase-3 (P10)/CASP3 antibody (PA1302-1). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-11-25


I was wanting to use your anti-Caspase-3 (P10)/CASP3 antibody for ICC for human jejunal mucosa on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human jejunal mucosa identification?

S. Johnson

Verified customer

Asked: 2019-10-15


It shows on the product datasheet, PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody has been validated for IHC-P, ICC, WB on human tissues. We have an innovator award program that if you test this antibody and show it works in human jejunal mucosa in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-10-15


Can you help my question with product PA1302-1, anti-Caspase-3 (P10)/CASP3 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Verified Customer

Verified customer

Asked: 2019-06-04


We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2019-06-04


I appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for jejunal mucosa using anti-Caspase-3 (P10)/CASP3 antibody PA1302-1. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2018-12-03


Thanks for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2018-12-03


Will anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 work for ICC with jejunal mucosa?

K. Miller

Verified customer

Asked: 2018-10-31


According to the expression profile of jejunal mucosa, CASP3 is highly expressed in jejunal mucosa. So, it is likely that anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 will work for ICC with jejunal mucosa.

Boster Scientific Support

Answered: 2018-10-31


We are currently using anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 for human tissue, and we are satisfied with the IHC-P results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on pig tissues as well?

Verified Customer

Verified customer

Asked: 2018-02-12


The anti-Caspase-3 (P10)/CASP3 antibody (PA1302-1) has not been tested for cross reactivity specifically with pig tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-02-12


Is this PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody reactive to the isotypes of CASP3?

F. Roberts

Verified customer

Asked: 2017-07-25


The immunogen of PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody is A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-3(P10)(220-236aa CAMLKQYADKLEFMHIL). Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2017-07-25


I was wanting to use using your anti-Caspase-3 (P10)/CASP3 antibody for response to glucose studies. Has this antibody been tested with western blotting on lung cancer tissue? We would like to see some validation images before ordering.

V. Zhao

Verified customer

Asked: 2016-12-02


Thank you for your inquiry. This PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody is validated on intestinal cancer tissue, hela cell lysate, smmc cell lysate, lung cancer tissue. It is guaranteed to work for IHC-P, ICC, WB in human. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2016-12-02


Would PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

M. Baker

Verified customer

Asked: 2015-04-15


It shows on the product datasheet, PA1302-1 anti-Caspase-3 (P10)/CASP3 antibody as been validated on ICC. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2015-04-15


See below the WB image, lot number and protocol we used for jejunal mucosa using anti-Caspase-3 (P10)/CASP3 antibody PA1302-1. Please let me know if you require anything else.

G. Jones

Verified customer

Asked: 2015-01-12


Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2015-01-12


Is there a BSA free version of anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 available?

C. Gonzalez

Verified customer

Asked: 2013-12-04


We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2013-12-04


Will anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 work on dog ICC with tongue?

M. Li

Verified customer

Asked: 2013-11-05


Our lab technicians have not tested anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 on dog. You can run a BLAST between dog and the immunogen sequence of anti-Caspase-3 (P10)/CASP3 antibody PA1302-1 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated dog samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in dog tongue in ICC, you can get your next antibody for free.

Boster Scientific Support

Answered: 2013-11-05


We ordered your anti-Caspase-3 (P10)/CASP3 antibody for WB on jejunal mucosa in the past. I am using human, and I plan to use the antibody for ICC next. I am interested in examining jejunal mucosa as well as t-cell in our next experiment. Could give a recommendation on which antibody would work the best for ICC?

P. Jones

Verified customer

Asked: 2013-09-23


I looked at the website and datasheets of our anti-Caspase-3 (P10)/CASP3 antibody and it appears that PA1302-1 has been tested on human in both WB and ICC. Thus PA1302-1 should work for your application. Our Boster satisfaction guarantee will cover this product for ICC in human even if the specific tissue type has not been validated. We do have a comprehensive range of products for ICC detection and you can check out our website to find out more information about them.

Boster Scientific Support

Answered: 2013-09-23


My boss were happy with the WB result of your anti-Caspase-3 (P10)/CASP3 antibody. However we have been able to see positive staining in cervix carcinoma erythroleukemia cytoplasm. using this antibody. Is that expected? Could you tell me where is CASP3 supposed to be expressed?

T. Lewis

Verified customer

Asked: 2013-07-04


Based on literature, cervix carcinoma erythroleukemia does express CASP3. Generally CASP3 expresses in cytoplasm. Regarding which tissues have CASP3 expression, here are a few articles citing expression in various tissues:
Cervix carcinoma, and Erythroleukemia, Pubmed ID: 23186163
Lymph, Pubmed ID: 15489334
T-cell, Pubmed ID: 7983002, 7774019
Tongue, Pubmed ID: 14702039

Boster Scientific Support

Answered: 2013-07-04


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