Anti-Caspase-6 CASP6 Antibody

Product Name

Anti-Caspase-6 CASP6 Antibody

View all CASP6 Antibodies

SKU/Catalog Number

A02631-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Caspase-6 CASP6 Antibody (Catalog # A02631-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Storage & Handling

Caspase-6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Caspase-6 CASP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02631-1)

Host

Rabbit

Contents

Caspase-6 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Caspase-6 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Caspase-6. The immunogen is located within amino acids 160 - 210 of Caspase-6.

Cross-reactivity

Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.

Reactive Species

A02631-1 is reactive to CASP6 in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

33.3 kDa

Background of CASP6

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-6 is an executioner caspase that was identified based on its homology with human caspases 2 and 3 as well as the C. elegans cell death protein CED-3. It possesses two isoforms, of which only the longer form possesses protease activity. Caspase-6 is highly expressed in adult brain and may play a role in several neuronal pathologies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02631-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Casp-6 antibody can be used for the detection of Caspase-6 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 1 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information CASP6

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