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- Table of Contents
Caspase-6 Antibodies
AND CASP6 ELISA kits, Caspase-6 Proteins
Many biological assays use antibodies to detect Caspase-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-6 antibodies...
Designing a Western blot for Caspase-6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CASP6 Western Blot GuideCASP6 Infographic by Boster Bio
All CASP6 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IHC, WB
$370
Cat # PA1441
100 μg/vial
Cat # PA1441
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02631
100 μl
Cat # M02631
100 μl
Human, Mouse, Rat
IHC, WB
$370
Cat # M02631-4
100 µl/vial
Cat # M02631-4
100 µl/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M02631-2
100 μl
Cat # M02631-2
100 μl
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A02631S257-1
100ul
Cat # A02631S257-1
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC1975
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1975
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1087
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1087
1 kit, containing one 96-well plate and all necessary reagents
CASP6 Overview
Facts about Caspase-6.
Caspase-6 (CASP6)
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, in addition to lamins.
Overexpression promotes programmed cell death. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP6 |
| Uniprot: | P55212 |
| Entrez: | 839 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
Apoptotic protease Mch-2; CASP6; CASP-6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; Caspase6; Caspase-6; EC 3.4.22; Mch2; MCH2EC 3.4.22.59
Molecular Weight
Mass (kDA):
33.31 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q25 |
| Sequence: | 4; NC_000004.12 (109688628..109703445, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Alzheimer's Disease
- Carcinoma
- Leukemia
- Huntington Disease
- Malignant Neoplasm Of Breast
- Malignant Paraganglionic Neoplasm
- Nerve Degeneration
- Neurodegenerative Disorders
- Mammary Neoplasms
- Tissue Adhesions
- Glioma
Interacting Proteins
- CASP3
- SATB1
Pathways
- Cell Death
- Proteolysis
- Pathogenesis
- Localization
- Induction Of Apoptosis
- Programmed Cell Death
- Cell Cycle
- Apoptotic Process
- Cell Proliferation
- Cell Differentiation
- Translation
- Neuroprotection
- Cellular Homeostasis
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Deacetylation
- Acetylation
Research Areas
- Apoptosis
- Cancer
- Caspases
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP6
bosterbio.com/bosterbio-gene-info-cards/CASP6
References
PMID: 7796396 by Fernandes-Alnemri T., et al. Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.
PMID: 8900201 by Srinivasula S.M., et al. The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.