Click image to see more details
Product Info Summary
| SKU: | PA2245 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-CAT1/SLC7A1 Antibody
SKU/Catalog Number
PA2245
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-CAT1/SLC7A1 Antibody catalog # PA2245. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CAT1/SLC7A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2245)
Host
Rabbit
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CAT1, different from the related mouse and rat sequences by four amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2245 is reactive to SLC7A1 in Human
Applications
PA2245 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
73 kDa
Calculated molecular weight
67.638kDa
Background of CAT1
High affinity cationic amino acid transporter 1, also called solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (SLC7A1) or ATRC1 is a protein that in humans is encoded by the SLC7A1 gene. This gene is mapped to 13q12.3. It acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor and plays a role in the Na+-independent y+ cationic amino acid transport system. This gene is high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Validation Images & Assay Conditions
Click image to see more details
Anti-CAT1 antibody, PA2245, Western blotting
Lane 1: Human Placenta Tissue Lysate
Lane 2: HELA Cell Lysate
Lane 3: SKOV-3 Cell Lysate
Lane 4: HT1080 Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For SLC7A1 (Source: Uniprot.org, NCBI)
Gene Name
SLC7A1
Full Name
High affinity cationic amino acid transporter 1
Weight
67.638kDa
Superfamily
amino acid-polyamine-organocation (APC) superfamily
Alternative Names
amino acid transporter, cationic 1; ATRC1; ATRC1ERR; CAT1; CAT-1System Y+ basic amino acid transporter; Ecotropic retroviral leukemia receptor homolog; ecotropic retroviral receptor; Ecotropic retrovirus receptor homolog; HCAT1; high affinity cationic amino acid transporter 1; REC1L; REC1LCAT1; SLC7A1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; Solute carrier family 7 member 1 SLC7A1 ATRC1, CAT-1, ERR, HCAT1, REC1L solute carrier family 7 member 1 high affinity cationic amino acid transporter 1|CAT1|amino acid transporter, cationic 1|ecotropic retroviral leukemia receptor homolog|ecotropic retroviral receptor|ecotropic retrovirus receptor homolog|solute carrier family 7 (cationic amino acid transporter, y+ system), member 1|system Y+ basic amino acid transporter
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC7A1, check out the SLC7A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC7A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CAT1/SLC7A1 Antibody (PA2245)
Hello CJ!
No publications found for PA2245
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Customer Reviews
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Customer Q&As
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Find answers in Q&As, reviews.
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4 Customer Q&As for Anti-CAT1/SLC7A1 Antibody
Question
See below the WB image, lot number and protocol we used for leukemic t-cell using anti-CAT1/SLC7A1 antibody PA2245. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2018-05-03
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2018-05-03
Question
Our lab want to know about to test anti-CAT1/SLC7A1 antibody PA2245 on human leukemic t-cell for research purposes, then I may be interested in using anti-CAT1/SLC7A1 antibody PA2245 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
D. Krishna
Verified customer
Asked: 2014-12-15
Answer
The products we sell, including anti-CAT1/SLC7A1 antibody PA2245, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2014-12-15
Question
I appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for leukemic t-cell using anti-CAT1/SLC7A1 antibody PA2245. Let me know if you need anything else.
B. Thomas
Verified customer
Asked: 2014-04-28
Answer
I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2014-04-28
Question
We are currently using anti-CAT1/SLC7A1 antibody PA2245 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on feline tissues as well?
L. Evans
Verified customer
Asked: 2013-03-27
Answer
The anti-CAT1/SLC7A1 antibody (PA2245) has not been tested for cross reactivity specifically with feline tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2013-03-27
