Anti-Cathelicidin CAMP Antibody

Product Name

Anti-Cathelicidin CAMP Antibody

View all CAMP Antibodies

SKU/Catalog Number

A05475

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Cathelicidin CAMP Antibody (Catalog # A05475). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Storage & Handling

Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Cathelicidin CAMP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05475)

Host

Rabbit

Contents

Cathelicidin Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the center of the human Cathelicidin. The immunogen is located within amino acids 50 - 100 of Cathelicidin.

Reactive Species

A05475 is reactive to CAMP in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

19.3 kDa

Background of CAMP

One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05475 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information CAMP

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