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Product Info Summary
| SKU: | A11125 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CAZIP MTUS2 Antibody
SKU/Catalog Number
A11125
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CAZIP MTUS2 Antibody (Catalog # A11125). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
CAZIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CAZIP MTUS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11125)
Host
Rabbit
Contents
CAZIP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
CAZIP antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human CAZIP. The immunogen is located within amino acids 1300 - 1350 of CAZIP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ATG2B antibody is predicted to not cross-react with other ATG2A.
Reactive Species
A11125 is reactive to MTUS2 in Human, Mouse
Applications
A11125 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
150.195kDa
Background of MTUS2
CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CAZIP antibody can be used for detection of CAZIP by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of CAZIP in mouse heart tissue with CAZIP antibody at 5 μg/mL.
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Immunofluorescence of CAZIP in mouse heart tissue with CAZIP antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MTUS2 (Source: Uniprot.org, NCBI)
Gene Name
MTUS2
Full Name
Microtubule-associated tumor suppressor candidate 2
Weight
150.195kDa
Alternative Names
Cardiac zipper protein; CAZIPTracking protein of 150 kDa; KIAA0774+TIP of 150 kDa; microtubule associated tumor suppressor candidate 2; Microtubule plus-end tracking protein TIP150; TIP150microtubule-associated tumor suppressor candidate 2 MTUS2 CAZIP, ICIS, KIAA0774, TIP150 microtubule associated scaffold protein 2 microtubule-associated tumor suppressor candidate 2|+TIP of 150 kDa|cardiac zipper protein|microtubule associated tumor suppressor candidate 2|microtubule plus-end tracking protein TIP150|tracking protein of 150 kDa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MTUS2, check out the MTUS2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MTUS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CAZIP MTUS2 Antibody (A11125)
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No publications found for A11125
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