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Product Info Summary
| SKU: | A10890 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-CCG8 CACNG8 Antibody
SKU/Catalog Number
A10890
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CCG8 CACNG8 Antibody catalog # A10890. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CCG8 CACNG8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10890)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CCG8 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A10890 is reactive to CACNG8 in Human, Mouse, Rat
Applications
A10890 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
43.313kDa
Background of CACNG8
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.
Hastie C.J., Biochem. J. 347:845-855(2000).
Zhang W., Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Mural R.J., Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CACNG8 (Source: Uniprot.org, NCBI)
Gene Name
CACNG8
Full Name
Voltage-dependent calcium channel gamma-8 subunit
Weight
43.313kDa
Superfamily
PMP-22/EMP/MP20 family
Alternative Names
CACNG6; calcium channel, voltage-dependent, gamma subunit 8; FLJ16240; FLJ30598; Neuronal voltage-gated calcium channel gamma-8 subunit; voltage-dependent calcium channel gamma-8 subunit CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 voltage-dependent calcium channel gamma-8 subunit|TARP gamma-8|calcium channel, voltage-dependent, gamma subunit 8|neuronal voltage-gated calcium channel gamma-8 subunit|transmembrane AMPAR regulatory protein gamma-8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CACNG8, check out the CACNG8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CACNG8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CCG8 CACNG8 Antibody (A10890)
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No publications found for A10890
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