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- Table of Contents
CCND1 antibody (M00149) performs well in WB and shows reactivity with Human, Mouse.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 14 Publications
Filter:
All lanes : Anti-CCND1 at dilution
Lane 1: MCF-7 whole cell lysate
Lane 2: HT-1080 whole cell lysate
Lane 3: L929 whole cell lysate
Lane 4: NIH/3T3 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Lane 1: MCF-7 whole cell lysate
Lane 2: HT-1080 whole cell lysate
Lane 3: L929 whole cell lysate
Lane 4: NIH/3T3 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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Anti-CCND1 Antibody
CCND1 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse | Mouse | WB |
Recommend Dilution
Application
Dilution
Species
WB: 1:2000
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-CCND1 Antibody
View all CCND1 Antibodies
View all CCND1 Antibodies
Uniprot
Gene ID
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1849CT557.93.5
Isotype
IgG1,κ
Immunogen
This antibody is generated from a mouse immunized with a recombinant protein from human.
Calculated Molecular Weight
33.7 kDa
Background of CCND1
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.
Cite This Product
Anti-CCND1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00149)
Publications
Application:
Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a
PMID: 26902620
The expression of AEG-1 and Cyclin D1 in human bladder urothelial carcinoma and their clinicopathological significance
PMID: 26885058
Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2
PMID: 26837415
CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment
PMID: 26526388
Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats
PMID: 26483688
Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and metastasis of osteosarcoma cells
PMID: 27274275
He H, Chen K, Wang F, Zhao L, Wan X, Wang L, Mo Z. Int J Mol Med. 2015 Jun;35(6):1587-95. Doi: 10.3892/Ijmm.2015.2160. Epub 2015 Mar 31. Mir-204-5P Promotes The Adipogenic Differentiation Of Human Adipose-Derived Mesenchymal Stem Cells By Modulati...
PMID: 25847080
Wu Y, Tao Y, Chen Y, Xu W. Plos One. 2012;7(11):E48917. Doi: 10.1371/Journal.Pone.0048917. Epub 2012 Nov 7. Rhoc Regulates The Proliferation Of Gastric Cancer Cells Through Interaction With Iqgap1.
PMID: 23145020
Du Mj, Chen Xd, Zhou Xl, Wan Yj, Lan B, Zhang Cz, Cao Y. Plos One. 2014 Jun 6;9(6):E99052. Doi: 10.1371/Journal.Pone.0099052. Ecollection 2014. Estrogen Induces Vav1 Expression In Human Breast Cancer Cells.
PMID: 24905577
Huang B, Lu Ys, Li X, Zhu Zc, Li K, Liu Jw, Zheng J, Hu Zl. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2179-84. Ecollection 2014. Androglobin Knockdown Inhibits Growth Of Glioma Cell Lines.
PMID: 24966926
Liu H, Yan Zq, Li B, Yin Sy, Sun Q, Kou Jj, Ye D, Ferns K, Liu Hy, Liu Sl. J Ovarian Res. 2014 Sep 5;7:87. Doi: 10.1186/S13048-014-0087-1. Reduced Expression Of Sox7 In Ovarian Cancer: A Novel Tumor Suppressor Through The Wnt/??-Catenin Signaling ...
PMID: 25297608
Liu J, Ma J, Wu Z, Li W, Zhang D, Han L, Wang F, Reindl Km, Wu E, Ma Q. Bmc Cancer. 2014 Sep 20;14:686. Doi: 10.1186/1471-2407-14-686. Arginine Deiminase Augments The Chemosensitivity Of Argininosuccinate Synthetase-Deficient Pancreatic Cancer Cel...
PMID: 25240403
Zhang H, Zhao B, Huang C, Meng Xm, Bian Eb, Li J. Plos One. 2014 May 2;9(5):E95520. Doi: 10.1371/Journal.Pone.0095520. Ecollection 2014. Melittin Restores Pten Expression By Down-Regulating Hdac2 In Human Hepatocelluar Carcinoma Hepg2 Cells.
PMID: 24788349
Li K, Zhu Zc, Liu Yj, Liu Jw, Wang Ht, Xiong Zq, Shen X, Hu Zl, Zheng J. Int J Clin Exp Pathol. 2013 Sep 15;6(11):2460-7. Ecollection 2013. Zfx Knockdown Inhibits Growth And Migration Of Non-Small Cell Lung Carcinoma Cell Line H1299.
PMID: 24228108
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Product Promise
We promise Anti-CCND1 Antibody performs excellently in relevant applications for WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
M00149
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 4, 2026