Anti-CD218b IL18RAP Antibody

Product Name

Anti-CD218b IL18RAP Antibody

View all IL18RAP Antibodies

SKU/Catalog Number

A06457

Size

100μl

Form

Liquid

Description

Boster Bio Anti-CD218b IL18RAP Antibody catalog # A06457. Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CD218b IL18RAP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06457)

Host

Rabbit

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Clone Number

6C12

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 291-340.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06457 is reactive to IL18RAP in Human

Applications

A06457 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

68.31kDa

Background of IL18RAP

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Microtubules are polymers of tubulin, which exist as heterodimers of alpha-tubulin and beta-tubulin. NEDD1 (neural precursor expressed, developmentally down-regulated protein1; also called GCP-WD) is a centrosomal protein that in mammals associates with the gamma-tubulin ring complex. Gamma-TuRC is critical for initiation, or nucleation, of the microtubule assembly. In association with this complex, NEDD1 plays an important role in targeting the gamma-TuRC complex to the site of microtubule nucleation and to the mitotic spindle. These events are essential for proper bipolar spindle formation and mitotic progression. Given the casual link between improper spindle function and tumorigenesis, characterization of Nedd1 function will be important to better understand various mechanisms underlying mitotic regulation, chromosome segregation, and cancer development.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC-P, 1:50-300

Validation Images & Assay Conditions

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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.

Gene/Protein Information For IL18RAP (Source: Uniprot.org, NCBI)

Alternative Names

CD218a; IL-1 R5; IL-1 Rrp; IL-18 R alpha; IL-18 R1; IL18R alpha; IL18R1; IL-18Ra IL18RAP ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB interleukin 18 receptor accessory protein interleukin-18 receptor accessory protein|CD218 antigen-like family member B|IL-18 receptor accessory protein|IL-18 receptor beta|cluster of differentiation w218b|interleukin-1 receptor 7|interleukin-18 receptor beta

For more info on IL18RAP, check out the IL18RAP Infographic

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In this infographic, you will see the following information for IL18RAP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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