Anti-CD62P/SELP Antibody

P-Selectin/CD62P antibody

Boster Bio Anti-CD62P/SELP Antibody catalog # PA1715. Tested in IHC, WB applications. This antibody reacts with Human. Cited in 2 publication(s).

Product Info Summary

SKU: PA1715
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-CD62P/SELP Antibody

View all P-Selectin/CD62P Antibodies

SKU/Catalog Number

PA1715

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CD62P/SELP Antibody catalog # PA1715. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CD62P/SELP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1715)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human CD62P.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1715 is reactive to SELP in Human

Applications

PA1715 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

140 kDa

Calculated molecular weight

90.834kDa

Background of P-Selectin/CD62P

P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For SELP (Source: Uniprot.org, NCBI)

Gene Name

SELP

Full Name

P-selectin

Weight

90.834kDa

Superfamily

selectin/LECAM family

Alternative Names

CD62P antigen; CD62P; FLJ45155; GMP140; GRMP; PADGEM; PADGEMantigen CD62); PSEL; P-Selectin; selectin P (granule membrane protein 140kDa, antigen CD62); SELP SELP CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL selectin P P-selectin|CD62 antigen-like family member P|GMP-140|granule membrane protein 140|granule membrane protein 140kDa|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|platelet alpha-granule membrane protein|selectin P (granule membrane protein 140kDa, antigen CD62)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SELP, check out the SELP Infographic

SELP infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SELP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1715 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Shu G,Lu C,Wang Z,Du Y,Xu X,Xu M,Zhao Z,Chen M,Dai Y,Weng Q,Fang S,Fan K,Liu D,Du Y,Ji J. Fucoidan-based micelles as P-selectin targeted carriers for synergistic treatment of acute kidney injury. Nanomedicine. 2020 Nov 27:102342.doi:10.1016/j.nano.2020.10
Species: Human,Mouse
PA1715 usage in article: APP:WB, SAMPLE:HUVECS, DILUTION:NA

Plasma Vitamin D Status and Its Correlation with Risk Factors of Thrombosis, P-selectin and hs-CRP Level in Patients with Venous Thromboembolism; the First Study of Iranian Population

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1 Customer Q&As for Anti-CD62P/SELP Antibody

Question

Do you have the IHC staining images generated by this anti-CD62P antibody for activated platelets?

Verified Customer

Verified customer

Asked: 2020-02-07

Answer

No we do not.

Boster Scientific Support

Answered: 2020-02-07

Order DetailsPrice
PA1715

100μg

$370
PA1715-10ug

10μg sample (liquid)

$99
PA1715-Biotin

100 μg Biotin conjugated

$570
PA1715-Cy3

100 μg Cy3 conjugated

$570
PA1715-Dylight488

100 μg Dylight488 conjugated

$570
PA1715-Dylight550

100 μg Dylight550 conjugated

$570
PA1715-Dylight594

100 μg Dylight594 conjugated

$570
PA1715-FITC

100 μg FITC conjugated

$570
PA1715-HRP

100 μg HRP conjugated

$570
PA1715-APC

100 μg APC conjugated

$670
PA1715-PE

100 μg PE conjugated

$670
PA1715-carrier-free

Carrier Free

$370

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