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- Table of Contents
P-selectin Antibodies
AND SELP ELISA kits, P-selectin Proteins
Many biological assays use antibodies to detect P-selectin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P-selectin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P-selectin antibodies...
Designing a Western blot for P-selectin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SELP Western Blot GuideSELP Infographic by Boster Bio
All SELP Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK0506
96 wells/kit, with removable strips.
Cat # EK0506
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0505
96 wells/kit, with removable strips.
Cat # EK0505
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03691-3
100 μg/vial
Cat # A03691-3
100 μg/vial
Human
ELISA
$500
Cat # EZ0505
5 plates/kit
Cat # EZ0505
5 plates/kit
Human
ELISA
$499
Cat # FEK0505
96 wells/kit, with removable strips.
Cat # FEK0505
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0506
96 wells/kit, with removable strips.
Cat # FEK0506
96 wells/kit, with removable strips.
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # A03676-1
100 μg/vial
Cat # A03676-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A03696-2
100 µg/vial
Cat # A03696-2
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03684-2
100 μg/vial
Cat # A03684-2
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01241-1
100 μg/vial
Cat # A01241-1
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03674-4
100 μg/vial
Cat # A03674-4
100 μg/vial
Mouse
ELISA
$500
Cat # EZ0506
5 plates/kit
Cat # EZ0506
5 plates/kit
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03696-1
100 µg/vial
Cat # A03696-1
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03688-2
100 μg/vial
Cat # A03688-2
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03678-2
100 µg/vial
Cat # A03678-2
100 µg/vial
Human, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01242-3
100 μg/vial
Cat # A01242-3
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03674-3
100 μg
Cat # M03674-3
100 μg
Human, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03674-2
100 μg
Cat # M03674-2
100 μg
SELP Overview
Facts about P-selectin.
P-selectin (SELP)
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes.
The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the first steps in inflammation through interaction with SELPLG.
Gene Information
| Human | |
|---|---|
| Gene Name: | SELP |
| Uniprot: | P16109 |
| Entrez: | 6403 |
Family
| Belongs to: |
|---|
| selectin/LECAM family |
Alternative Names
CD62P antigen; CD62P; FLJ45155; GMP140; GRMP; PADGEM; PADGEMantigen CD62); PSEL; P-Selectin; selectin P (granule membrane protein 140kDa, antigen CD62); SELP
Molecular Weight
Mass (kDA):
90.834 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q24.2 |
| Sequence: | 1; NC_000001.11 (169588849..169630125, complement) |
Tissue Specificity
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Inflammation
- Malignant Neoplasms
- Atherosclerosis
- Cardiovascular Diseases
- Neoplasms
- Heart Diseases
- Inflammatory Response
- Malignant Head And Neck Neoplasm
- Von Willebrand Disease
- Infarction
- Myocardial Infarction
- Head And Neck Neoplasms
Interacting Proteins
- SELPLG
Pathways
- Cell Adhesion
- Platelet Activation
- Pathogenesis
- Inflammatory Response
- Platelet Aggregation
- Aging
- Cell Activation
- Immune Response
- Endothelial Cell Activation
- Angiogenesis
- Transport
- Hypersensitivity
- Virulence
PTMs
- Phosphorylation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SELP
bosterbio.com/bosterbio-gene-info-cards/SELP
References
PMID: 2466574 by Johnston G.I., et al. Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation.
PMID: 7684381 by Fujimoto T., et al. P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage.
13 Publications of Boster P-selectin Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2016.5294, Effects of the eukaryotic initiation factor 6 gene on expression levels of infla...
- PubMed ID: 10.1016/j.colsurfb.2012.02.018, Fabrication of biomolecule-PEG micropattern on titanium surface and its effects ...
- PubMed ID: 10.1007/s10753-014-9918-x, Simvastatin Inhibits Inflammation in Ischemia-Reperfusion Injury
- PubMed ID: -, Nesibe,E.Y.,& KONUKOĞLU,D.(2021).Plasma Levels of Soluble P-Selectin, Beta-Thro...
- PubMed ID: 33046059, Guo J,Li M,Yang Y,Zhang L,Zhang LW,Sun QY.Pretreatment with atorvastatin amelior...
- PubMed ID: 32934963, Zhang R,Ji J,Zhou X,Li R.Irisin Pretreatment Protects Kidneys against Acute Kidn...
- PubMed ID: 33253922, Shu G,Lu C,Wang Z,Du Y,Xu X,Xu M,Zhao Z,Chen M,Dai Y,Weng Q,Fang S,Fan K,Liu D,D...
- PubMed ID: 24734087, Plasma Vitamin D Status and Its Correlation with Risk Factors of Thrombosis, P-s...
- PubMed ID: 28633041, Fayed, M.A., Abdel-Hady, H.E., Hafez, M.M., Salama, O.S., & Al-Tonbary, Y.A. (20...
- PubMed ID: 24992835, Tun X, Yasukawa K, Yamada K. Free Radic Biol Med. 2014 Sep;74:108-17. Doi: 10.10...
- PubMed ID: 22998024, Yasukawa K, Tokuda H, Tun X, Utsumi H, Yamada K. Free Radic Res. 2012 Dec;46(12)...
- PubMed ID: 26038476, Li L, Ben Y, Yuan S, Liu A, Wu H, Xu J, Zhang X. Emerg Microbes Infect. 2013 Jul...
- PubMed ID: 22391529, Zhong M, He B, Yang J, Bao R, Zhang Y, Zhou D, Chen Y, Li L, Han C, Yang Y, Sun ...
*More publications can be found for each product on its corresponding product page