Anti-CDK5RAP1 Antibody

CDK5RAP1 antibody

Boster Bio Anti-CDK5RAP1 Antibody catalog # A09177. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A09177
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-CDK5RAP1 Antibody

View all CDK5RAP1 Antibodies

SKU/Catalog Number

A09177

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CDK5RAP1 Antibody catalog # A09177. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CDK5RAP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09177)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human CBLN1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A09177 is reactive to CDK5RAP1 in Human, Mouse, Rat

Applications

A09177 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

67.689kDa

Background of CDK5RAP1

Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the formation and maintenance of parallel fiber and Purkinje cell synapses. When parallel fibers make contact with Purkinje spines, CBLN1 interaction with GRID2 triggers the recruitment of NRXN1 and secretory vesicles to the sites of contact. NRXN1-CBLN1-GRID2 signaling induces presynaptic morphological changes, which may further accumulate pre- and postsynaptic components to promote bidirectional maturation of parallel fiber - Purkinje cell functionnally active synapses by a positive feedback mechanism. Required for CBLN3 export from the endoplasmic reticulum and secretion By similarity.The cerebellin peptide exerts neuromodulatory functions. Directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release By similarity.

Urade Y., Proc. Natl. Acad. Sci. U.S.A. 88:1069-1073(1991).
Ota T., Nat. Genet. 36:40-45(2004).
Mural R.J., Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:100

Validation Images & Assay Conditions

Gene/Protein Information For CDK5RAP1 (Source: Uniprot.org, NCBI)

Gene Name

CDK5RAP1

Full Name

CDK5 regulatory subunit-associated protein 1

Weight

67.689kDa

Superfamily

methylthiotransferase family

Alternative Names

C20orf34; C42; CDK5 activator-binding protein C42; CDK5 regulatory subunit associated protein 1; CDK5 regulatory subunit-associated protein 1; CDK5RAP1.3; CDK5RAP1.4; CGI-05; chromosome 20 open reading frame 34; HSPC167 CDK5RAP1 C20orf34, C42, CGI-05, HSPC167 CDK5 regulatory subunit associated protein 1 mitochondrial tRNA methylthiotransferase CDK5RAP1|CDK5 activator-binding protein C42|mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase|mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CDK5RAP1, check out the CDK5RAP1 Infographic

CDK5RAP1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CDK5RAP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A09177-100ul

100ul

$405

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A09177
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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