Product Info Summary
SKU: | M06475 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Mouse |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Cerberus CER1 Monoclonal Antibody
SKU/Catalog Number
M06475
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Cerberus CER1 Monoclonal Antibody catalog # M06475. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cerberus CER1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M06475)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
9D6
Isotype
IgG
Immunogen
Purified recombinant fragment of human Cerberus expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M06475 is reactive to CER1 in Human
Applications
M06475 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
30.084kDa
Background of CER1
Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). EsrpP-1 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry analysis of paraffin-embedded human gastric cancer (left) and normal gastric tissues (right) with DAB staining using Cerberus monoclonal antibody.
Click image to see more details
Western blot analysis using Cerberus monoclonal antibody against CER1 (aa18-267) -hIgGFc transfected HEK293 cell lysate (1).
Protein Target Info & Infographic
Gene/Protein Information For CER1 (Source: Uniprot.org, NCBI)
Gene Name
CER1
Full Name
Cerberus
Weight
30.084kDa
Superfamily
DAN family
Alternative Names
CER1; cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily); Cerberus 1; cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis); cerberus; cerberus-related 1; Cerberus-related protein; DAN domain family member 4; DAND4; MGC119894; MGC119895; MGC96951 CER1 DAND4 cerberus 1, DAN family BMP antagonist cerberus|DAN domain family member 4|cerberus 1, cysteine knot superfamily, homolog|cerberus-related 1|cerberus-related protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CER1, check out the CER1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CER1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cerberus CER1 Monoclonal Antibody (M06475)
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No publications found for M06475
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