Product Info Summary
| SKU: | A11588 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CLEC2A Antibody
SKU/Catalog Number
A11588
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CLEC2A Antibody (Catalog # A11588). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
CLEC2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CLEC2A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11588)
Host
Rabbit
Contents
CLEC2A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CLEC2A antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CLEC2A. The immunogen is located within the first 50 amino acids of CLEC2A.
Cross-reactivity
CLEC2A antibody is human specific. Two alternatively spliced transcript variants have been observed.
Reactive Species
A11588 is reactive to CLEC2A in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
20.0 kDa
Background of CLEC2A
CLEC2A (C-type lectin domain family 2 member A), also known as PILAR (proliferation-induced lymphocyte-associated receptor) is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that contains one C-type lectin domain in its extracellular region and belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Manipulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11588 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CLEC2A antibody can be used for detection of CLEC2A by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of CLEC2A in K562 cell lysate with CLEC2A antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of CLEC2A in K562 cells with CLEC2A antibody at 20 μg/mL.
Specific Publications For Anti-CLEC2A Antibody (A11588)
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