Product Info Summary
SKU: | A11588 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CLEC2A Antibody
SKU/Catalog Number
A11588
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CLEC2A Antibody (Catalog # A11588). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
CLEC2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CLEC2A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11588)
Host
Rabbit
Contents
CLEC2A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
CLEC2A antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CLEC2A. The immunogen is located within the first 50 amino acids of CLEC2A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CLEC2A antibody is human specific. Two alternatively spliced transcript variants have been observed.
Reactive Species
A11588 is reactive to CLEC2A in Human
Applications
A11588 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
19.972kDa
Background of CLEC-2A
CLEC2A (C-type lectin domain family 2 member A), also known as PILAR (proliferation-induced lymphocyte-associated receptor) is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that contains one C-type lectin domain in its extracellular region and belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Manipulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CLEC2A antibody can be used for detection of CLEC2A by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of CLEC2A in K562 cell lysate with CLEC2A antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of CLEC2A in K562 cells with CLEC2A antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CLEC2A (Source: Uniprot.org, NCBI)
Gene Name
CLEC2A
Full Name
C-type lectin domain family 2 member A
Weight
19.972kDa
Alternative Names
CLEC2A C-type lectin domain family 2, member A ; CLEC2A; CLEC-2A; KACL; PILAR; UNQ5792 CLEC2A INPE5792, KACL, PILAR, UNQ5792 C-type lectin domain family 2 member A C-type lectin domain family 2 member A|keratinocyte-associated C-type lectin|proliferation-induced lymphocyte-associated receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CLEC2A, check out the CLEC2A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CLEC2A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CLEC2A Antibody (A11588)
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No publications found for A11588
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