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Product Info Summary
| SKU: | A11251 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CMPK2 Antibody
SKU/Catalog Number
A11251
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CMPK2 Antibody (Catalog # A11251). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CMPK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CMPK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11251)
Host
Rabbit
Contents
CMPK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2. The immunogen is located within amino acids 370 - 420 of CMPK2.
Cross-reactivity
Multiple isoforms of CMPK2 are known to exist.
Reactive Species
A11251 is reactive to CMPK2 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
49.4 kDa
Background of CMPK2
UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11251 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CMPK2 in rat lung tissue lysate with CMPK2 antibody at 1 μg/mL
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Immunofluorescence of CMPK2 in human lung tissue with CMPK2 antibody at 20 μg/mL.
Specific Publications For Anti-CMPK2 Antibody (A11251)
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