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Product Info Summary
| SKU: | A11251 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CMPK2 Antibody
SKU/Catalog Number
A11251
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CMPK2 Antibody (Catalog # A11251). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CMPK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CMPK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11251)
Host
Rabbit
Contents
CMPK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2. The immunogen is located within amino acids 370 - 420 of CMPK2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of CMPK2 are known to exist.
Reactive Species
A11251 is reactive to Cmpk2 in Human, Mouse, Rat
Applications
A11251 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
50.036kDa
Background of TYKi
UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CMPK2 in rat lung tissue lysate with CMPK2 antibody at 1 μg/mL
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Immunofluorescence of CMPK2 in human lung tissue with CMPK2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Cmpk2 (Source: Uniprot.org, NCBI)
Gene Name
Cmpk2
Full Name
UMP-CMP kinase 2, mitochondrial
Weight
50.036kDa
Superfamily
thymidylate kinase family
Alternative Names
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; cytidylate kinase 2; EC 2.7.4.14; mitochondrial UMP-CMP kinase; mitochondrial; thymidine monophosphate kinase 2; thymidylate kinase family LPS-inducible member; TMPK2; TYKi; UMP-CMPK2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cmpk2, check out the Cmpk2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cmpk2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CMPK2 Antibody (A11251)
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No publications found for A11251
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Customer Reviews
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