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Product Info Summary
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Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94)
Boster Bio Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94) catalog # MA1030. Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1030)
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Human collagen type IV.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross-reactivity with other proteins
MA1030 is reactive to COL4A1 in Human
MA1030 is guaranteed for IHC Boster Guarantee
Background of Collagen IV alpha 1
Collagen IV is comprised of a third chain (alpha-3) together with the 2 classical ones, alpha-1 and alpha-2. COL4A3 gene is localized to 2q36-q37 by analysis of somatic cell hybrids and by in situ hybridization. The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Human
Validation Images & Assay Conditions
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Anti-Collagen, Type IV antibody (monoclonal), MA1030, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Gene/Protein Information For COL4A1 (Source: Uniprot.org, NCBI)
Collagen alpha-1(IV) chain
type IV collagen family
alpha-1 chain; Arresten; COL4A1 NC1 domain; COL4A1; collagen alpha-1(IV) chain; Collagen IV alpha 1; collagen IV, alpha-1 polypeptide; collagen, type IV, alpha 1; Collagen-4; EC 3.4.23; EC 126.96.36.199 COL4A1 BSVD, BSVD1s, PADMAL, RATOR, COL4A1 collagen type IV alpha 1 chain collagen alpha-1(IV) chain|COL4A1 NC1 domain|arresten|collagen IV, alpha-1 polypeptide|collagen of basement membrane, alpha-1 chain*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on COL4A1, check out the COL4A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for COL4A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
MA1030 has been cited in 8 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats
Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor ?-Independent Pathway
MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elastic fibers correlate with disease progression in a hamster model of tongue cancer
Zhu B, Xu T, Yuan J, Guo X, Liu D. Plos One. 2013 Sep 19;8(9):E76282. Doi: 10.1371/Journal.Pone.0076282. Ecollection 2013. Transcriptome Sequencing Reveals Differences Between Primary And Secondary Hair Follicle-Derived Dermal Papilla Cells Of The...
Zhang Z, Wu F, Zheng F, Li H. Nephron Exp Nephrol. 2010;116(1):E11-21. Doi: 10.1159/000314669. Epub 2010 May 21. Adenovirus-Mediated Decorin Gene Transfection Has Therapeutic Effects In A Streptozocin-Induced Diabetic Rat Model.
Wen D, Huang X, Zhang M, Zhang L, Chen J, Gu Y, Hao Cm. Plos One. 2013 Dec 3;8(12):E82336. Doi: 10.1371/Journal.Pone.0082336. Ecollection 2013. Resveratrol Attenuates Diabetic Nephropathy Via Modulating Angiogenesis.
Xu L, Zheng N, He Q, Li R, Zhang K, Liang T. Phytomedicine. 2013 Oct 15;20(13):1172-9. Doi: 10.1016/J.Phymed.2013.06.008. Epub 2013 Jul 13. Puerarin, Isolated From Pueraria Lobata (Willd.), Protects Against Hepatotoxicity Via Specific Inhibition O...
Zhang H, Teng X, Liu Z, Zhang L, Liu Z. J Exp Clin Cancer Res. 2015 Feb 12;34:16. Doi: 10.1186/S13046-015-0132-Y. Gene Expression Profile Analyze The Molecular Mechanism Of Cxcr7 Regulating Papillary Thyroid Carcinoma Growth And Metastasis.
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