Product Info Summary
| SKU: | A09709 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-COMMD7 Antibody
SKU/Catalog Number
A09709
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-COMMD7 Antibody (Catalog # A09709). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
COMMD7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-COMMD7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09709)
Host
Rabbit
Contents
COMMD7 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
COMMD7 antibody was raised against a 19 amino acid peptide near the center of human COMMD7. The immunogen is located within amino acids 90 - 140 of COMMD7.
Cross-reactivity
COMMD7 antibody is human, mouse and rat reactive. Multiple transcript variants encoding different isoforms have been found for COMMD7.
Reactive Species
A09709 is reactive to COMMD7 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
22.5 kDa
Background of COMMD7
COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1). It associates with the NF-kB complex and suppresses its transcriptional activity (2). COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3). COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4). COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09709 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
COMMD7 antibody can be used for detection of COMMD7 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of COMMD7 in mouse spleen tissue lysate with COMMD7 antibody at 1 μg/ml.
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Immunohistochemistry of COMMD7 in human spleen tissue with COMMD7 antibody at 5 μg/mL.
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Immunofluorescence of COMMD7 in human spleen tissue with COMMD7 antibody at 20 μg/mL.
Specific Publications For Anti-COMMD7 Antibody (A09709)
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