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Product Info Summary
| SKU: | M00961-3 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA (Cap) |
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Product info
Product Name
Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7)
SKU/Catalog Number
M00961-3
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) catalog # M00961-3. Tested in ELISA applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00961-3)
Host
Mouse
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality
Monoclonal
Clone Number
8H7
Isotype
Mouse IgG1
Immunogen
E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
M00961-3 is reactive to CST3 in Human
Calculated molecular weight
15.8 kDa
Background of CST3
Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00961-3 is guaranteed for ELISA (Cap) Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA (Cap), 1-5μg/ml
Validation Images & Assay Conditions
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Sandwich ELISA - Recombinant human Cystatin C/CST3 protein standard curve.
Use in combination with reagents from Human Cystatin C/CST3 ELISA Kit EZ-Set (DIY Antibody Pairs) (EZ0678).
Specific Publications For Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) (M00961-3)
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