Anti-Cytokeratin Peptide 18 KRT18 Antibody (Monoclonal, 35K72)

Anti-Cytokeratin Peptide 18 KRT18 Antibody (Monoclonal, 35K72)
View all KRT18 Antibodies

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3.

35K72

The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Intermediate filaments (IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18 (KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis.