- Table of Content
Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
|intermediate filament family|
|Sequence:||12; NC_000012.12 (52948871..52952906)|
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Cytoplasm, perinuclear region. Nucleus, nucleolus.
Reactivity: Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat
Applications: Flow Cytometry, IF, IHC, ICC, WB
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