Anti-DDB2 Antibody Picoband™

XPE/DDB2 antibody

Boster Bio Anti-DDB2 Antibody Picoband™ catalog # A01430-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A01430-2
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, Flow Cytometry, WB

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Product Name

Anti-DDB2 Antibody Picoband™

View all XPE/DDB2 Antibodies

SKU/Catalog Number

A01430-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-DDB2 Antibody Picoband™ catalog # A01430-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DDB2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01430-2)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human DDB2 recombinant protein (Position: Q10-R424).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01430-2 is reactive to DDB2 in Human

Applications

A01430-2 is guaranteed for ELISA, Flow Cytometry, WB Boster Guarantee

Observed Molecular Weight

48 kDa

Calculated molecular weight

47.864kDa

Background of XPE/DDB2

DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For DDB2 (Source: Uniprot.org, NCBI)

Gene Name

DDB2

Full Name

DNA damage-binding protein 2

Weight

47.864kDa

Superfamily

WD repeat DDB2/WDR76 family

Alternative Names

damage-specific DNA binding protein 2 (48kD); damage-specific DNA binding protein 2, 48kDa; Damage-specific DNA-binding protein 2; DDB p48 subunit; DDB2; DDBB; DNA damage-binding protein 2; FLJ34321; UV-damaged DNA-binding protein 2; UV-DDB 2; UV-DDB2; xeroderma pigmentosum group E protein; XP5; XPE/DDB2 DDB2 DDBB, UV-DDB2, XPE damage specific DNA binding protein 2 DNA damage-binding protein 2|DDB p48 subunit|UV-DDB 2|UV-damaged DNA-binding protein 2|damage-specific DNA binding protein 2, 48kDa|xeroderma pigmentosum group E protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DDB2, check out the DDB2 Infographic

DDB2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DDB2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01430-2

100μg

$370
A01430-2-10ug

10μg sample (liquid)

$99
A01430-2-Biotin

100 μg Biotin conjugated

$570
A01430-2-Cy3

100 μg Cy3 conjugated

$570
A01430-2-Dylight488

100 μg Dylight488 conjugated

$570
A01430-2-Dylight550

100 μg Dylight550 conjugated

$570
A01430-2-Dylight594

100 μg Dylight594 conjugated

$570
A01430-2-FITC

100 μg FITC conjugated

$570
A01430-2-HRP

100 μg HRP conjugated

$570
A01430-2-APC

100 μg APC conjugated

$670
A01430-2-PE

100 μg PE conjugated

$670
A01430-2-carrier-free

Carrier Free

$370

More conjugates/formats

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A01430-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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