Neutrophil defensin 1 Antibodies

AND DEFA1 ELISA kits, Neutrophil defensin 1 Proteins

Many biological assays use antibodies to detect Neutrophil defensin 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neutrophil defensin 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neutrophil defensin 1 antibodies...

We validate the specificity of these antibodies to Neutrophil defensin 1 by testing them on tissues known to express DEFA1 positively and negatively. Browse below to find the DEFA1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Neutrophil defensin 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the DEFA1 Western Blot Guide

DEFA1 Infographic by Boster Bio

All DEFA1 Products

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Product

Figures

Specificity

Applications

Price

Human alpha-defensin 1/DEFA1 ELISA Kit PicoKine®

1 Citations

Human

ELISA

$750
Cat # EK1514
96 wells/kit, with removable strips.

Human DEFA1 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human

ELISA

$500
Cat # EZ1514
For 5 plates, 96 wells each

Anti-Alpha Defensin 1/DEFA1 Antibody Picoband®

Western blot analysis of Alpha Defensin 1 using anti-Alpha Defensin 1 antibody (A10546)

Human, Rat

$370
Cat # A10546
100 μg/vial

alpha Defensin 1 (DEFA1) (NM_004084) Human Over-expression Lysate

Human

$628
Cat # LS001667
20 µg, 100 µg

alpha Defensin 1 (DEFA1B) (NM_001042500) Human Over-expression Lysate

Human

$628
Cat # LS728358
20 µg, 100 µg

DEFA1 Overview

Facts about Neutrophil defensin 1.

DEFA1 3D structure. Source: alphafold

Neutrophil defensin 1 (DEFA1)

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria.

Defensins are believed to kill microbes by permeabilizing their plasma membrane. .

Gene Information

Human
Gene Name:	DEFA1
Uniprot:	P59665
Entrez:	1667

Family

Belongs to:

alpha-defensin family

Alternative Names

alpha 2; alphaDefensin 1; alpha-Defensin 1; DEF1; DEF1DEFA1B; DEFA1; DEFA2; defensin, alpha 1, myeloid-related sequence; defensin, alpha 1HP-1; HNP-1; HNP-1HP1; HP1; MRS; MRSMGC138393; myeloid-related sequence; neutrophil defensin 1

Molecular Weight

Mass (kDA):
10.201 kDA

Genomic Context


Human

Location:	8p23.1
Sequence:	8; NC_000008.11 (6977649..6980120, complement)

Subcellular Localizations

Secreted.

Diseases

Inflammation
Intestinal Diseases
Immunologic Deficiency Syndromes
Actinomycetales Infections
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Communicable Diseases
Colitis
Infective Disorder
Horse Diseases
Adenoma

Behcet Syndrome
Latent Tuberculosis
Lung Diseases
Ulcer
Coinfection
Lung Diseases, Obstructive

Pathways

Pathogenesis
Gene Conversion
Translation
Tissue Remodeling
Cell Differentiation
Immune Response
Metaphase
Tissue Homeostasis

Inflammatory Response
Secretion

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DEFA1

References

PMID: 3174637 by Daher K.A., et al. Isolation and characterization of human defensin cDNA clones.

PMID: 3370315 by Mars W.M., et al. A myeloid-related sequence that localizes to human chromosome 8q21.1- 22.